Effect of sucralose--alone or bulked with maltodextrin and/or dextrose--on plaque pH in humans

Caries Research
C MeyerowitzR F Raubertas

Abstract

Sucralose is a safe, intensely sweet, noncaloric sucrose derivative that has been shown to be noncariogenic. The purpose of the present study was to compare the effects on plaque pH in vivo of sucralose in iced tea (alone or bulked with maltodextrin or with maltodextrin/dextrose) with sucrose in iced tea. Fourteen subjects, with DMFT > 7 and an acidogenic plaque, participated in the study. Plaque pH response to one of five solutions: unsweetened tea, tea with sucralose (final concentration 0.007% by weight), tea with sucralose/maltodextrin (final concentrations 0.007% and 0.59% by weight, respectively), tea with sucralose/maltodextrin/dextrose (final concentrations 0.007, 0.018 and 0.57% by weight, respectively) and tea with sucrose (final concentration 4.7% by weight); was assessed in five experimental sessions. All solutions, except the unsweetened tea, had a sweetness equivalent to 2 teaspoons of sucrose in 6 OZ of beverage. Using a touch electrode, plaque pH was measured at baseline and at specific time intervals up to 60 min after rinsing with the test solution for 1 min. Comparisons between groups were done for minimum pH, delta pH, and area under the pH curve (AUC), by using the nonparametric Friedman's test and the Wilc...Continue Reading

Citations

Aug 25, 2001·Journal of Dentistry·G R Al-KhatibK J Toumba
Feb 13, 2016·Archives of Oral Biology·Clarissa Gewehr SteguesLina Naomi Hashizume
May 26, 2009·Regulatory Toxicology and Pharmacology : RTP·V Lee Grotz, Ian C Munro
Feb 24, 2005·Journal of Dentistry·A J Preston, W M Edgar
Sep 10, 2017·Nutrition Journal·Szimonetta LohnerJoerg J Meerpohl

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