Effect of sugarcane biopolymer in vocal fold of rabbits. Comparative study with calcium hydroxyapatite

Acta Cirúrgica Brasileira
Silvio José de VasconcelosDomingos Hiroshi Tsuji

Abstract

To compare the inflammatory reaction caused by the injection of a sugarcane biopolymer (SCB) into the vocal fold of rabbits with that caused by calcium hydroxyapatite (CaH). CaH (Radiesse(r)) and SCB gel were injected respectively into the right and left vocal cords of thirty rabbits. The rabbits were distributed into two equal groups and sacrificed at three and twelve weeks after injection. We then evaluated the intensity of the inflammatory reaction, plus levels of neovascularization, fibrogenesis and inflammatory changes in the vocal mucosa. The vocal cords injected with CaH had a stronger inflammatory reaction by giant cells in both study periods. The SCB group had a more intense inflammatory involvement of polymorphonuclear cells three weeks after injection. SCB caused a higher level of neovascularization compared with CaH three weeks after the procedure. Whereas calcium hydroxyapatite triggers a more intense and lasting inflammatory reaction mediated by giant cells, sugarcane biopolymer causes a greater response from polymorphonuclear leukocytes, as well as higher levels of vneoascularization three weeks after injection.

References

Jan 9, 2001·The Journal of Investigative Dermatology. Symposium Proceedings·M G TonnesenR A Clark
Aug 28, 2004·Journal of Voice : Official Journal of the Voice Foundation·Clark A Rosen, Apurva A Thekdi
Oct 7, 2004·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Peter C Belafsky, Gregory N Postma
Feb 6, 2007·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Clark A RosenAndrew McWhorter
Jun 19, 2009·Journal of Voice : Official Journal of the Voice Foundation·David P LauMurray D Morrison
Mar 18, 2011·Ear, Nose, & Throat Journal·Carlos M Rivera-Serrano, Libby J Smith
Nov 8, 2011·Journal of Voice : Official Journal of the Voice Foundation·Rima A DeFattaRobert T Sataloff
Oct 19, 2012·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Tianjie ShenSanjay Morzaria
Nov 28, 2012·Otolaryngologic Clinics of North America·Pavan S Mallur, Clark A Rosen
Dec 22, 2012·Arquivos brasileiros de oftalmologia·Francisco de Assis Cordeiro-BarbosaSidcley Bernardino-Araújo
Nov 23, 2013·Otolaryngologic Clinics of North America·Laureano A Giraldez-Rodriguez, Michael Johns
Aug 26, 2014·Brazilian Journal of Otorhinolaryngology·Rodrigo Augusto de Souza LeãoSilvio José de Vasconcelos

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Citations

Feb 4, 2016·Acta Cirúrgica Brasileira·Taciana Cavalcanti de AbreuBelmiro Cavalcanti do Egito Vasconcelos
Dec 29, 2020·The Laryngoscope·Anna Maria Stefanie BuchbergerKatharina Storck

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