Effect of swimming exercise on three-dimensional trabecular bone microarchitecture in ovariectomized rats

Journal of Applied Physiology
Yong-In JuMasao Fukunaga

Abstract

Swimming is generally considered ineffective for increasing bone mass in humans, at least compared with weight-bearing sports. However, swimming exercise has sometimes been shown to have a strong positive effect on bone mass in small animals. This study investigated the effects of swimming on bone mass, strength, and microarchitecture in ovariectomized (OVX) rats. OVX or sham operations were performed on 18-wk-old female Fisher 344 rats. Rats were randomly divided into four groups: sham sedentary (Sham-CON), sham swimming exercised (Sham-SWI), OVX sedentary (OVX-CON), and OVX swimming exercised (OVX-SWI). Rats in exercise groups performed swimming in a water bath for 60 min/day, 5 days/wk, for 12 wk. Bone mineral density (BMD) in right femurs was analyzed using dual-energy X-ray absorptiometry. Three-dimensional trabecular architecture at the distal femoral metaphysis was analyzed using microcomputed tomography (μCT). Geometrical properties of diaphyseal cortical bone were evaluated in the midfemoral region using μCT. The biomechanical properties of femurs were analyzed using three-point bending. Femoral BMD was significantly decreased following ovariectomy. This change was suppressed by swimming. Trabecular bone thickness, num...Continue Reading

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Citations

Aug 3, 2017·International Journal of Molecular Sciences·Zhihao ChenAirong Qian
Mar 26, 2019·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Victoria L GremmingerCharlotte L Phillips
Oct 17, 2017·Journal of Exercise Nutrition & Biochemistry·Yun-Seok KangJeong-Seok Kim
Jul 19, 2017·Journal of Exercise Nutrition & Biochemistry·Yun-Seok KangJae-Cheol Kim

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