PMID: 11605928Oct 19, 2001Paper

Effect of synchronized intermittent mandatory ventilation on respiratory workload in infants after cardiac surgery

Anesthesiology
H ImanakaT Yagihara

Abstract

Synchronized intermittent mandatory ventilation (SIMV) is commonly used in infants and adults. However, few investigations have examined how SIMV reduces respiratory workload in infants. The authors evaluated how infants' changing respiratory patterns when reducing SIMV rate increased respiratory load. The authors also investigated whether SIMV reduces infant respiratory workload in proportion to the rate of mandatory breaths and which rate of SIMV provides respiratory workloads similar to those after tracheal extubation. When 11 post-cardiac surgery infants aged 2-11 months were to be weaned with SIMV, the authors randomly applied five levels of mandatory breathing: 0, 5, 10, 15, and 20 breaths/min. All patients underwent ventilation with SIMV mode: pressure control ventilation, 16 cm H2O; inspiratory time, 0.8 s; triggering sensitivity, 0.6 l/min; and positive endexpiratory pressure, 3 cm H2O. After establishing steady-state conditions at each SIMV rate, arterial blood gases were analyzed, and esophageal pressure, airway pressure, and airflow were measured. Inspiratory work of breathing, pressure-time products, and the negative deflection of esophageal pressure were calculated separately for assisted breaths, for spontaneous ...Continue Reading

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Citations

Oct 3, 2013·The Journal of Clinical Investigation·Samit GhoshSolomon Fiifi Ofori-Acquah
Jan 24, 2004·Pediatric Research·Jennifer BeckChrister Sinderby
Oct 18, 2005·Intensive Care Medicine·Brigham C WillisChristopher J L Newth
Nov 29, 2005·Anesthesiology Clinics of North America·Stephen Stayer, Olutoyin Olutoye

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