PMID: 3757940Sep 1, 1986Paper

Effect of systemic estrogen on seizure susceptibility in the immature animal

Epilepsia
W A Schultz-KrohnG L Holmes

Abstract

Estrogens have previously been reported to be proconvulsants in adult animals. This study evaluated the effects of acute, high-dose estrogen administration on rate of kindling in immature rats. No significant differences in rate of kindling between the estrogen-treated rats and controls were noted. This study, using the kindling model, demonstrates that estradiol does not have a significant effect on the development of seizures in the immature animal.

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Citations

Mar 22, 2003·Neuroscience Letters·Mehdi Saberi, Mohammad H Pourgholami
Jan 1, 1992·Epilepsia·M J Morrell
Oct 23, 2013·Pharmacological Reports : PR·Mohammad N AlamAftab Ahmad
Aug 9, 2005·Pharmacology, Biochemistry, and Behavior·Cheryl A Frye, Madeline E Rhodes
Jan 19, 2007·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·Jana Velísková

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