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Effect of T-2 mycotoxin on rat liver mitochondria electron transport system

Toxicon : Official Journal of the International Society on Toxinology

Jan 1, 1983

J G Pace

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Abstract

The in vitro and in vivo effects of T-2 mycotoxin on electron transport in rat liver mitochondria were investigated. T-2 toxin (2.2 mM) inhibited oxygen consumption by 40% in ADP-coupled and DNP-uncoupled mitochondria using either succinate or pyridine-nucleotide linked substrates. Stud...read more

Mentioned in this Paper

Pyridines
T-2 Toxin
Pyruvate Measurement
Electron Transport
Succinates
Mitochondria, Liver
Sesquiterpenes
T-2 Toxin, alpha,4 beta-Isomer
Oxidation
Pyruvate
Paper Details
References
  • References5
  • Citations29
  • References5
  • Citations29
123

Feeds With Similar Papers

Electron Transport Chain Biology

The electron transport chain (ETC) facilitates the transfer of electrons through redox while transferring protons across the membrane into the intermembrane space. This feed focuses on the structure and mechanism of the ETC as well as mitochondrial disorders caused by defects in the oxidative phosphorylation pathway.

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Effect of T-2 mycotoxin on rat liver mitochondria electron transport system

Toxicon : Official Journal of the International Society on Toxinology

Jan 1, 1983

J G Pace

PMID: 6648984

DOI: 10.1016/0041-0101(83)90273-8

Abstract

The in vitro and in vivo effects of T-2 mycotoxin on electron transport in rat liver mitochondria were investigated. T-2 toxin (2.2 mM) inhibited oxygen consumption by 40% in ADP-coupled and DNP-uncoupled mitochondria using either succinate or pyridine-nucleotide linked substrates. Stud...read more

Mentioned in this Paper

Pyridines
T-2 Toxin
Pyruvate Measurement
Electron Transport
Succinates
Mitochondria, Liver
Sesquiterpenes
T-2 Toxin, alpha,4 beta-Isomer
Oxidation
Pyruvate

Feeds With Similar Papers

Electron Transport Chain Biology

The electron transport chain (ETC) facilitates the transfer of electrons through redox while transferring protons across the membrane into the intermembrane space. This feed focuses on the structure and mechanism of the ETC as well as mitochondrial disorders caused by defects in the oxidative phosphorylation pathway.

Related Papers

Toxicon : Official Journal of the International Society on Toxinology

T-2 mycotoxin inhibits mitochondrial protein synthesis

Toxicon : Official Journal of the International Society on ToxinologyJanuary 1, 1988
J G PaceW J Canterbury
Toxicon : Official Journal of the International Society on Toxinology

Ultrastructural effects of T-2 mycotoxin on rat hepatocytes in vitro

Toxicon : Official Journal of the International Society on ToxinologyJanuary 1, 1986
L R Trusal, J C O'Brien
Paper Details
References
  • References5
  • Citations29
  • References5
  • Citations29
123

Download from

Publisher
PubMed
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