Effect of tannery effluent on oxidative status of brain structures and liver of rodents

Environmental Science and Pollution Research International
Felipe dos Santos MoysésIonara Rodrigues Siqueira

Abstract

Oxidative stress has been considered as a central mechanism of toxicity induced by xenobiotics. Previously, it was demonstrated that mice exposed to tannery effluent showed an anxiety-like behavior, without any comparable behavioral effects in rats. The aim of the present study was to investigate the impact of tannery wastewater on oxidative status in in vitro and in vivo assays with two mammal species, mice and rats. Specifically, homogenates of two brain areas and the liver were incubated with tannery wastewater; reactive species and lipid peroxidation levels and antioxidant enzyme activities were detected. In addition, the effects of in vivo exposure of mice to tannery effluents on and lipid peroxidation levels and the total reactive antioxidant capacity in brain areas and liver. Brain areas, the hippocampus and frontal cortex, and the liver of mice exposed to tannery wastewater showed oxidative stress. Our data suggest that divergent species-dependent hepatic enzymes adaptations, such as glutathione peroxidase and glutathione S-transferase activities, induced by tannery effluent could explain previous behavioral findings.

References

Jan 1, 1978·Methods in Enzymology·J A Buege, S D Aust
Jan 1, 1992·Free Radical Research Communications·E LissiM D Del Castillo
Aug 1, 1993·Free Radical Biology & Medicine·J D AdamsD Shah
May 1, 1993·The American Journal of Clinical Nutrition·B Halliwell, S Chirico
May 15, 1997·The Biochemical Journal·R T DeanM J Davies
Jan 28, 1999·Methods in Molecular Biology·K Yagi
Jan 9, 2001·American Journal of Industrial Medicine·J A TicknerM Rossi
Mar 15, 2001·Proceedings of the National Academy of Sciences of the United States of America·M Ramos-GomezT W Kensler
May 23, 2001·Archives of Biochemistry and Biophysics·P EvelsonE A Lissi
Nov 9, 2001·The International Journal of Neuroscience·M R Avila-CostaS Rivas-Arancibia
Jan 22, 2002·Biological Psychiatry·Richard J Davidson
Aug 29, 2003·Journal of the Air & Waste Management Association·Vinod TarePurnendu Bose
Jan 7, 2004·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·Lauretta M S ChanBarry H Hirst
May 12, 2004·Current Pharmaceutical Design·Carlo M BergaminiCarlo Cervellati
Jul 1, 2004·Neuroscience and Biobehavioral Reviews·D M BannermanJ Feldon
Dec 16, 2004·Environmental Science & Technology·Francesca MaradonnaOliana Carnevali
Aug 23, 2005·Environmental and Molecular Mutagenesis·Hifzur R SiddiqueD Kar Chowdhuri
Oct 26, 2005·Nature·Iiris HovattaCarrolee Barlow
Feb 17, 2006·Clinica Chimica Acta; International Journal of Clinical Chemistry·Anusuya Devi MuthuswamyPanneerselvam Chinnakannu
Jan 31, 2007·Ecotoxicology and Environmental Safety·M PrabakaranR Dinakaran Michael
Mar 31, 2007·European Journal of Pharmacology·Jaouad BouayedRachid Soulimani
Jul 12, 2008·The FEBS Journal·Rogerio MargisMarcia Margis-Pinheiro
Dec 31, 2008·Mutation Research·Rodrigo FrancoMihalis I Panayiotidis
Dec 24, 2010·Ecotoxicology and Environmental Safety·Valeria TiginiGiovanna Cristina Varese
Mar 23, 2011·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Fatma M El-Demerdash
Jun 15, 2011·Neurotoxicology and Teratology·Ionara Rodrigues SiqueiraSimone Stülp
Aug 23, 2012·Ecotoxicology and Environmental Safety·Karine BertoldiIonara Rodrigues Siqueira
Sep 25, 2012·Free Radical Biology & Medicine·Kalavathi DasuriJeffrey N Keller
Dec 4, 2012·Biochimica Et Biophysica Acta·Philip G Board, Deepthi Menon
May 28, 2013·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Jeonghoon HanJae-Seong Lee
Feb 20, 2014·Physiology & Behavior·Felipe dos Santos MoysésIonara Rodrigues Siqueira
May 31, 2014·Water Research·Janet Y M TangBeate I Escher
Dec 3, 2015·Brazilian Journal of Biology = Revista Brasleira De Biologia·N JaegerA L Ziulkoski
Oct 4, 2016·Environmental Science and Pollution Research International·Abraão Tiago Batista GuimarãesGuilherme Malafaia

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.