Effect of temperature on electrical resonance in leopard frog saccular hair cells

Journal of Neurophysiology
M S Smotherman, P M Narins

Abstract

Leopard frog saccular hair cells exhibit an electrical resonance in response to a depolarizing stimulus that has been proposed to contribute to the tuning properties of the frog sacculus by acting as an electrical band-pass filter. With the whole cell patch-clamp technique, we have investigated the effect of temperature on electrical resonances in isolated saccular hair cells, and we have described the effects of temperature on the currents and channel kinetics underlying electrical resonance. A hair cell's onset resonant frequency in response to a constant depolarizing current pulse increases linearly with temperature at a rate of 11 Hz/1 degrees C, exhibiting a mean Q10 of 1.7 between 15 and 35 degrees C. However, offset resonant frequencies continue to double every 10 degrees C, exhibiting a mean Q10 of 2.1. If steady-state voltage during the stimulus is held constant, all oscillatory frequencies increase with a mean Q10 of 2.1. The average level of steady-state depolarization during a +150-pA depolarizing current pulse decreases with increasing temperature (-6 mV from 15 to 25 degrees C). This temperature-dependent reduction of the steady-state membrane potential causes a shift in the voltage-dependent channel kinetics to s...Continue Reading

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Citations

Nov 18, 2015·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Ian C HallDarcy B Kelley
Oct 1, 2013·The European Physical Journal. Special Topics·Gani S AssanovAlexander B Neiman
Jul 15, 2011·The Journal of Experimental Biology·Natasha MhatreRohini Balakrishnan
Jul 7, 1999·Hearing Research·M S Smotherman, P M Narins

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