Effect of tension-free vaginal tape operation on urethral closure function

Urology
Dieter KoelleStephan Kropshofer

Abstract

To evaluate whether the tension-free vaginal tape operation changes urethral hypermobility, funneling, and urethral urodynamic parameters in different parts of the urethra. We conducted a cohort study of our first 80 unselected female patients (age 36 to 78 years, median 53) undergoing a tension-free vaginal tape procedure. Urethral pressure profile measurements were done before and 6 and 12 months after the operation. Lateral cystography was performed before and after surgery in 50 patients. Of the 80 women, 29 had previously undergone prolapse or incontinence surgery. Parameter-free techniques were used for statistical evaluation. Five patients were lost to follow-up. On an intention-to-treat basis, 66% of the patients were objectively and subjectively cured, 20% were objectively dry but subjectively occasionally incontinent, and 14% had treatment failure. The maximal urethral closure pressure at rest showed no significant changes (median baseline and 6 and 12 months postoperatively, 44, 40, and 38 cm H(2)O, respectively). The pressure transmission ratio increased in the proximal urethra (median 107.5%, 122.5%, and 123.5% at baseline and 6 and 12 months postoperatively, respectively, P <0.05) and distal urethra (median 80%, 1...Continue Reading

References

Jun 1, 1996·Journal of Endourology·J L MostwinA Yang
Jan 1, 1996·International Urogynecology Journal and Pelvic Floor Dysfunction·U UlmstenG Varhos
Jul 30, 1999·British Journal of Obstetrics and Gynaecology·U UlmstenM Rezapour
Oct 29, 2000·International Urogynecology Journal and Pelvic Floor Dysfunction·A C Wang
Feb 13, 2001·Acta Obstetricia Et Gynecologica Scandinavica·T S LoY K Soong
Jul 14, 2001·International Urogynecology Journal and Pelvic Floor Dysfunction·M Rezapour, U Ulmsten
Sep 29, 2001·Obstetrics and Gynecology·N MutoneD Hale
Jul 13, 2002·BMJ : British Medical Journal·Karen WardUNKNOWN United Kingdom and Ireland Tension-free Vaginal Tape Trial Group
Sep 5, 2003·International Urogynecology Journal and Pelvic Floor Dysfunction·Emily S LukaczCharles W Nager

❮ Previous
Next ❯

Citations

Dec 3, 2008·International Urology and Nephrology·Bassem S Wadie, Ahmed S El-Hefnawy
Jul 19, 2006·International Urogynecology Journal and Pelvic Floor Dysfunction·Lena HarmsVolker Viereck
Feb 14, 2016·International Urogynecology Journal·Yasmine KhayyamiGunnar Lose
Apr 22, 2008·The Journal of Urology·John O L DeLanceyJames A Ashton-Miller
Mar 30, 2012·Neurourology and Urodynamics·Marie-Louise SaabyGunnar Lose
Oct 9, 2014·Neurourology and Urodynamics·Marie-Louise SaabyGunnar Lose
Mar 22, 2008·American Journal of Obstetrics and Gynecology·Yuko M KomesuJennifer Pohl
Jun 15, 2007·Current Opinion in Urology

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.