Effect of the degree of osteoporosis on the biomechanical anchoring strength of the sacral pedicle screws: an in vitro comparison between unaugmented bicortical screws and polymethylmethacrylate augmented unicortical screws

Spine
Xin-Ming ZhuangWilliam W Lu

Abstract

An in vitro laboratory study. (i) To evaluate the effect of osteoporotic degree in determining the strength of sacral screw fixation and (ii) to compare the strength of unaugmented bicortical pedicle screw and polymethylmethacrylate (PMMA) augmented unicortical pedicle screw in sacral fixation. Screw loosening is a clinical problem in lumbosacral fusions, especially in osteoporotic patients. To improve the screw anchoring strength of sacrum, bicortical and PMMA augmented sacral pedicle screw fixation techniques are widely used in clinical practice. However, the biomechanical strength of the bicortical and PMMA augmented sacral screw fixations remains undetermined in different degrees of osteoporosis. Twenty-five fresh osteoporotic cadavers were used in this study. According to the value of lumbar bone mineral density (BMD) assessed by DEXA, specimens were divided into 3 groups: group A (N=9): BMD=0.7 to 0.8 g/cm, group B (N=8): BMD=0.6 to 0.7 g/cm, and group C (N=8): BMD<0.6 g/cm. In each specimen, S1 pedicle screw was inserted bicortically on the left side, and S1 pedicle screw with PMMA augmentation was inserted unicortically on the right side of the sacrum. Following a dynamic cyclic loading from 30 to 250 N on the screw hea...Continue Reading

References

Jun 1, 1991·Spine·S MirkovicS R Garfin
May 1, 1995·Biomaterials·C M FlahiffR W Nicholas
Mar 1, 1997·The Journal of Bone and Joint Surgery. British Volume·H PihlajämakiO Böstman
Nov 20, 2002·Spine·Nathan H LebwohlTheodore A Wagner
Mar 17, 2006·Spine·Bonaventure B NguSteven C Ludwig
Jul 11, 2006·Journal of Spinal Disorders & Techniques·Cem YilmazNur Altinors
Jan 9, 2007·Clinical Biomechanics·William SterbaRahul Vaidya
Sep 12, 2007·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Ipek ErgurHamid Tayefi
Sep 11, 2008·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·S BeckerH Redl
Sep 17, 2008·Spine·Matthew D WaitesStephen M Belkoff

❮ Previous
Next ❯

Citations

Mar 23, 2013·Operative Orthopädie und Traumatologie·H KollerO Meier
May 3, 2011·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Ming-Hsien HuChien-Lin Liu
Jul 19, 2013·European Journal of Orthopaedic Surgery & Traumatology : Orthopédie Traumatologie·Hiroyuki Yoshihara
Feb 19, 2013·The Spine Journal : Official Journal of the North American Spine Society·Heiko KollerMichael Mayer
Jun 22, 2011·The Spine Journal : Official Journal of the North American Spine Society·William J AnderstJames D Kang
Oct 30, 2015·The Journal of the American Academy of Orthopaedic Surgeons·Theodore J ChomaDarrel S Brodke
Mar 24, 2015·The Spine Journal : Official Journal of the North American Spine Society·Benjamin D ElderTimothy F Witham
Jun 25, 2016·Injury·Christian von Rüden, Peter Augat
Sep 3, 2016·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Yong ZhangWei Tian
Apr 5, 2017·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Werner SchmoelzLuis Álvarez Galovich
Apr 23, 2016·Clinical Spine Surgery : a Spine Publication·Hamid HassanzadehAlan C Dalkin
Mar 22, 2013·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·Arslan K ArslanKudret Türeyen
Jun 28, 2020·Scientific Reports·Ming-Kai HsiehChing-Lung Tai
Mar 6, 2017·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·A AichmairM Farshad
May 10, 2017·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·William J AnderstJoon Y Lee
Mar 23, 2017·Clinical Spine Surgery : a Spine Publication·Matthew ColmanDarrel S Brodke
Aug 15, 2012·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·Teyfik Demir, Necip Camuşcuz
Nov 14, 2019·Dento Maxillo Facial Radiology·Zhe GuoXiaoguang Cheng

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.