Effect of the DTwP Haemophilus influenzae b conjugate vaccination in Mexico (1999-2007)

Archives of Medical Research
Patricia Gómez de León CrucesJose Ignacio Santos

Abstract

The introduction of type b Haemophilus influenzae (Hi b) conjugate vaccines for children as part of immunization schedules has led to a sharp drop in the incidence of Hi b disease. In 1999, the Haemophilus influenzae b DTwP-HB/Hi b vaccine was introduced into the primary immunization program in Mexico. There have been no studies evaluating the vaccine after the widespread immunization in our country. The immune response to Hi b vaccines in different countries varies both quantitatively and qualitatively. Replacement of Hi b strains is expected between pre- and post-vaccination eras. Documentation on these three aspects will be useful for decisions regarding the use of the vaccine. In this review, we show and discuss the potential benefits of vaccination with DTwP-HB/Hi b in Mexico in terms of our collected data obtained during the last 8 years on population genotype variations and on concentration and avidity of IgG antibodies. As the epidemiological follow-up data are missing, the evaluation of the results of these three types of studies, as a whole, allows clarification of the scenario of the protection after vaccination in Mexico, in absence of the drop in cases reports. These results reinforce the findings of postvaccinatio...Continue Reading

References

May 1, 1989·Reviews of Infectious Diseases·R Austrian
Jun 1, 1983·The Journal of Infectious Diseases·H KäyhtyP H Mäkelä
Mar 1, 1995·Journal of Clinical Pathology·A E AgbarakweH M Chapel
Jan 1, 1995·The Journal of Infectious Diseases·M L BarbourE R Moxon
Jul 27, 1996·Lancet·S K ObaroB M Greenwood
Oct 29, 2000·BMJ : British Medical Journal·D Kwiatkowski
Dec 24, 2002·Archives of Disease in Childhood. Fetal and Neonatal Edition·P ClarkeM J Robinson
May 10, 2003·Lancet·Ger T RijkersElisabeth A M Sanders
Apr 23, 2004·Infection and Immunity·Janet R GilsdorfBetsy Foxman
Sep 24, 2004·Immunology·Dominic F KellyAndrew J Pollard
May 7, 2005·The Pediatric Infectious Disease Journal·Laura L HammittJay C Butler
Sep 9, 2005·Clinical and Diagnostic Laboratory Immunology·Sandra Romero-SteinerGeorge M Carlone
Apr 7, 2006·Journal of Clinical Microbiology·Raymond S W TsangDennis K S Law
May 19, 2006·Emerging Infectious Diseases·Nik G JohnsonPaul T Heath
Jun 10, 2006·Epidemiologic Reviews·Robert Menzies, Peter McIntyre
Mar 14, 2007·Infection and Immunity·Zhigang JinRachel Schneerson
Dec 11, 2007·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Carlos Franco-ParedesJosé Ignacio Santos-Preciado
Jan 4, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Yeh Chen LeeAndrew J Pollard
May 23, 2009·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Marina Ulanova, Raymond S W Tsang

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bacterial Pneumonia (ASM)

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.

Bacterial Meningitis (ASM)

Bacterial meningitis continues to be an important cause of mortality and morbidity throughout the world. Here is the latest research.

Bacterial Meningitis

Bacterial meningitis continues to be an important cause of mortality and morbidity throughout the world. Here is the latest research.

Bacterial Pneumonia

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.