Effect of the F129L Mutation in Alternaria solani on Fungicides Affecting Mitochondrial Respiration

Plant Disease
J S PascheN C Gudmestad

Abstract

Isolates of Alternaria solani previously collected from throughout the Midwestern United States and characterized as being azoxystrobin sensitive or reduced sensitive were tested for sensitivity to the Quinone outside inhibitor (QoI) fungicides famoxadone and fenamidone and the carboxamide fungicide boscalid. All three fungicides affect mitochondrial respiration: famoxadone and fenamidone at complex III, and boscalid at complex II. A. solani isolates possessing reducedsensitivity to azoxystrobin also were less sensitive in vitro to famoxadone and fenamidone compared with azoxystrobin-sensitive isolates, but the shift in sensitivity was of lower magnitude, approximately 2- to 3-fold versus approximately 12-fold for azoxystrobin. The in vitro EC50 values, the concentration that effectively reduces germination by 50% relative to the untreated control, for sensitive A. solani isolates were significantly lower for famoxadone and azoxystrobin than for fenamidone and boscalid; whereas, for reduced-sensitive isolates, famoxadone EC50 values were significantly lower than all other fungicides. Isolates of A. solani with reducedsensitivity to azoxystrobin were twofold more sensitive in vitro to boscalid than were azoxystrobin-sensitive wi...Continue Reading

References

Jul 31, 2002·Pest Management Science·Dave W BartlettBob Parr-Dobrzanski
Apr 29, 1966·Science·B V Schmeling, M Kulka
Feb 1, 2004·Plant Disease·J S PascheN C Gudmestad

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Citations

Jun 26, 2007·Applied and Environmental Microbiology·Wei-Jen ChenMarie-France Corio-Costet
Jan 24, 2019·Plant Disease·Mitchell J Bauske, Neil C Gudmestad
Jan 24, 2019·Plant Disease·Mitchell J BauskeNeil C Gudmestad
Aug 25, 2015·Pest Management Science·Ana C KlosowskiGerd Stammler
Jul 1, 2013·Plant Disease·N C GudmestadJ S Pasche
Oct 1, 2007·Plant Disease·Herve F Avenot, Themis J Michailides
Oct 1, 2015·Plant Disease·J R StandishN Aboughanem-Sabanadzovic
Mar 20, 2012·Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes·Emil RekanovićMilica Mihajlović
Oct 4, 2008·Pest Management Science·Stefano Ff TorrianiHelge Sierotzki
Nov 17, 2011·Phytopathology·Melvin D BoltonGary A Secor
Jul 15, 2016·Environmental Science and Pollution Research International·Jacek BartlewiczHans Jacquemyn

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