Effect of the oral contraceptive pill on ligamentous laxity

Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine
Paul A MartineauMark L Burman

Abstract

Women are 4 to 8 times more likely to sustain a serious knee injury than their male counterparts. Previous studies have found that female sex steroids affect ligamentous tissue properties. The hypothesis is that there exists a difference in ligamentous laxity between oral contraceptive pill (OCP) users and nonusers. Blinded, single-factor, posttest-only control group design. McGill University Sport Medicine Clinic, Montreal, Que-bec, Canada. One hundred twenty-seven female McGill University varsity athletes. Participants filled out a screening questionnaire and underwent KT-1000 measurements by 1 blinded examiner. Exclusion criteria related to underlying knee pathology, and hormonal factors were identified with the questionnaire. Independent sample, 2-tailed t tests were performed on the nondominant knee data of the OCP users and nonusers. Mean anterior translations at 67 N were 3.00 +/- 1.04 mm for the OCP users and 3.86 +/- 1.72 mm for the nonusers (P = 0.011); at 89 N, 3.98 +/- 1.13 mm vs. 4.83 +/- 1.82 mm, respectively (P = 0.018). Mean anterior translations at 67 N were 2.95 +/- 0.93 mm for the non-menstruating OCP users and 3.86 +/- 1.72 mm for the nonusers (P = 0.008); at 89 N, 3.88 +/- 1.06 mm vs. 4.83 +/- 1.82 mm, resp...Continue Reading

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