Jul 1, 1977

Effect of the Y chromosome on the morphology of human F-chromatin under normal and pathological conditions

Tsitologiia
R I Kulikov

Abstract

Morphological peculiarities of brightly fluorescent chromatin (referred to as F-chromatin) in cell nuclei of buccal epithelium stained with propil-quinacrine mustard are studied in 94 healthy men and in 67 healthy women; in 4 men with 46,XYq--, I man with 46,XYq+; in 15 patients with the Kleinfelter syndrome (47,XXY) in 7 women with 46,XY and 5 males with 47,XYY. Diametre of F-chromatin bodies in buccal cells of healthy men varied within 0.9--0.2 mkm. Classification of types of interphase nuclei is proposed based on the rise, quantity and arrangement of F-chromatin bodies. The study of F-chromatin and X-chromatin showed independent behavior of these structures in cells of buccal smears obtained from 15 patients with the Kleinfelter syndrome.

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Mentioned in this Paper

Y Chromosome
Sex Chromosomes
Fluorescence
Sex Chromosome Aberrations
Cell Nucleus
Acrichine Yperite
Leukocytes
Heterochromatin
Sex Chromatin
Staining and Labeling

About this Paper

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