PMID: 7350205Jan 1, 1980

Effect of theophylline and terbutaline on immediate skin tests

The Journal of Allergy and Clinical Immunology
B E ChippsL M Lichtenstein

Abstract

A questionnaire survey of board-certified allergists revealed that conflicting ideas exist as to the effect that drugs such as theophylline and beta 2 agonists have an immediate skin tests. Approximately half of the respondents felt these drugs would obscure a skin response; the remainder would not withdraw the drugs prior to testing. As a result of this difference in opinion, we studied the effects of these drugs on skin tests in seven subjects taking terbutaline (5 mg three times daily) and 13 subjects taking theophylline (3 to 5 mg/kg every 6 hr). Neither an acute loading dose nor chronic administration of either drug singly produced significant changes in wheal size in response to histamine, ragweed, or grass allergens. We conclude that theophylline and terbutaline administered singly at these doses have no effect on immediate skin tests.

Citations

Apr 1, 1986·The Journal of Allergy and Clinical Immunology·R D Fairshter, W W Busse
Aug 21, 2013·International Journal of Pediatric Otorhinolaryngology·Keziban BulanCigdem Yilmaz Aydogmus
Sep 6, 2003·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Samuel L Hill, John H Krouse
May 16, 1998·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·J P SeeryA K Datta
Mar 1, 1988·Clinical Allergy·J B WarrenR W Fuller
Dec 1, 1980·The Journal of Pediatrics·F Leffert
Jan 1, 1984·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·V T Popa
Jul 1, 1982·Drug Intelligence & Clinical Pharmacy·J C McElnayD K Helling
Feb 1, 1989·British Journal of Clinical Pharmacology·J B WarrenC T Dollery
Jun 23, 2001·Allergologia et immunopathologia·C CuhadarogluF Erkan

Related Concepts

Asthma
Immediate Hypersensitivity
Hypersensitivity Skin Testing
Terbutalin von ct
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