PMID: 15374354Jan 1, 1993Paper

Effect of thermal inactivation and ATP on age related changes in hepatic glutamate dehydrogenase activity of male garden lizard

Archives of Gerontology and Geriatrics
B S Jena, B K Patnaik

Abstract

The total glutamate dehydrogenase (GDH) activity of the liver of the male garden lizard did not change during maturation (young to middle-aged) but showed a decline in later phase of the life span (middle-aged to old). On the other hand, the heat stable GDH activity increase during maturation and declined thereafter. The degree of thermal inactivation of the total GDH activity at 45 degrees +/- 1 degree C was not age-dependent. ATP stimulation of total GDH activity was about three times higher in old than in middle-aged lizards.

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