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Effect of thiocarbonyl compounds on alpha-naphthylisothiocyanate-induced hepatotoxicity and the urinary excretion of [35S]alpha-naphthylisothiocyanate in the rat

Toxicology and Applied Pharmacology

Mar 15, 1984

G J TraigerRobert P. Hanzlik

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Abstract

The effect of disulfiram (DSF), sodium diethyldithiocarbamate (DDTC), methyl diethyldithiocarbamate (Me-DDTC), and ethionamide on the hepatotoxic response of alpha-naphthylisothiocyanate (ANIT) was studied in the rat. The hyperbilirubinemic response of ANIT was significantly inhibited b...read more

Mentioned in this Paper

Disulfiram
1-Naphthylisothiocyanate
Antabus
Metazoa
Metabolic Inhibition
Portion of Urine
Ditiocarb, Tin(4+) Salt
Drug-Induced Acute Liver Injury
Excretory Function
Urinary Tract
Paper Details
References
  • References26
  • Citations3
123

Effect of thiocarbonyl compounds on alpha-naphthylisothiocyanate-induced hepatotoxicity and the urinary excretion of [35S]alpha-naphthylisothiocyanate in the rat

Toxicology and Applied Pharmacology

Mar 15, 1984

G J TraigerRobert P. Hanzlik

PMID: 6324415

DOI: 10.1016/0041-008x(84)90127-3

Abstract

The effect of disulfiram (DSF), sodium diethyldithiocarbamate (DDTC), methyl diethyldithiocarbamate (Me-DDTC), and ethionamide on the hepatotoxic response of alpha-naphthylisothiocyanate (ANIT) was studied in the rat. The hyperbilirubinemic response of ANIT was significantly inhibited b...read more

Mentioned in this Paper

Disulfiram
1-Naphthylisothiocyanate
Antabus
Metazoa
Metabolic Inhibition

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Paper Details
References
  • References26
  • Citations3
123

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