PMID: 591663Oct 1, 1977

Effect of thiocyanate on mammary gland growth in rats

The Journal of Dairy Research
H Pyska

Abstract

In growing rats from 3 weeks to 3 months old, 0.1% potassium thiocyanate (KSCN) decreased the plasma protein-bound iodine level by 47% and the total DNA in the mammary gland by 11%, but had no effect on the total RNA. Administration of thiocyanate in the form of 0.1, 0.3 and 0.5% KSCN during pregnancy and 14 d of lactation lowered the protein-bound iodine level by 48-66%, the total DNA by 11-47% and the total RNA by 14-63%, depending on the KSCN dosage. The 14-d-old litters of rats receiving thiocyanate weighed 4-41% less than those in the control group.

References

Dec 1, 1965·Acta Physiologica Scandinavica·L Ekman
Aug 1, 1974·The Journal of Endocrinology·S KikuyamaK Yamanouchi
Apr 1, 1961·Proceedings of the Society for Experimental Biology and Medicine·D R GRIFFITH, C W TURNER
Feb 1, 1963·Zeitschrift für Ernährungswissenschaft·E PIIRONEN, A I VIRTANEN
Jan 1, 1960·Proceedings of the Society for Experimental Biology and Medicine·R C MOON, C W TURNER
Sep 1, 1950·The Journal of Clinical Endocrinology and Metabolism·S B BARKER, M J HUMPHREY

Citations

Apr 1, 1980·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·H NagasawaK Shiota
Oct 1, 1985·International Journal of Peptide and Protein Research·S Watanabe, T Saito

Related Concepts

Serum Proteins
DNA, Double-Stranded
Iodine
Lactation, Prolonged
Udder
Plasma Protein Binding Capacity
Thiocyanates

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