PMID: 2126184May 1, 1990Paper

Effect of thrombolysis on the evolution of late potentials within 10 days of infarction

British Heart Journal
M EldarS Abboud

Abstract

Patients with late potentials in the signal averaged electrocardiogram are more at risk of lethal arrhythmias in the period after acute myocardial infarction. To test the effects of thrombolysis on the incidence and evolution of late potentials, 158 consecutive patients were prospectively studied during the first 10 days after acute myocardial infarction. The study population consisted of two groups: 93 control patients treated conservatively and 65 patients treated with intravenous thrombolysis. Recordings of signal averaged electrocardiogram were obtained within two days and 7-10 days after infarction. The incidence of late potentials in the first two days after infarction was not significantly different in the thrombolytic and control groups (14% v 11.8%). By 7-10 days the incidence of late potentials among patients who underwent thrombolysis remained unchanged (14%); however, it increased significantly in the control group (11.8% to 22.5%). Thus thrombolysis seems to reduce the evolution of late potentials within 10 days of infarction. Because the risk of fatal arrhythmias is higher in patients with late potentials this study may partly explain the reduced mortality after thrombolysis.

References

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Citations

Mar 1, 1993·Journal of the American College of Cardiology·F J Pashkow
Mar 1, 1992·Journal of the American College of Cardiology·S G EllisE J Topol
Sep 1, 1990·British Heart Journal·G BreithardtU Karbenn
Apr 15, 1995·Lancet·J M GlancyD P de Bono
Jun 1, 1996·Pacing and Clinical Electrophysiology : PACE·L A BeauregardP B Kurnik
Oct 1, 1992·Mayo Clinic Proceedings·J CurwinV Fuster
Nov 1, 1993·Pacing and Clinical Electrophysiology : PACE·B StrasbergS Sclarovsky
Sep 4, 2007·Progress in Cardiovascular Diseases·Gaetano Antonio Lanza
Nov 1, 1992·American Heart Journal·H L KennedyT A Buckingham
Jan 1, 1993·Progress in Cardiovascular Diseases·T R EngelS P Murphy
Jun 1, 1993·Current Problems in Cardiology·O Kjellgren, J A Gomes
Oct 30, 1998·The American Journal of Cardiology·E LomamaA Vacheron
Jul 1, 1996·Catheterization and Cardiovascular Diagnosis·R L QuigleyM H Salinger

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