Effect of thyroid volume on radioiodine therapy outcome in hyperthyroid cats

Journal of Feline Medicine and Surgery
Veerle VolckaertKathelijne Peremans

Abstract

Radioiodine therapy is commonly used in hyperthyroid cats and has a high success rate, ranging from 85-95%. As in humans, thyroid volume has been reported to influence radioiodine therapy outcome in hyperthyroid cats. The purpose of this study was to relate total thyroid volume, calculated by a newly constructed formula for feline patients (0.438 × length × width²), to the outcome of radioiodine therapy. To search for a correlation between total thyroid volume and therapy outcome, 167 hyperthyroid cats were included. Patients were categorised according to the administered radioiodine dose and therapy outcome. Our analysis did not show a significant relationship between an increasing total thyroid volume and the odds for a final low total thyroxine concentration (TT4; P = 0.3930) or a final hyperthyroid outcome (P = 0.0901). A significant relationship was found for an increase in the odds for a final low TT4 outcome with an increase in the number of foci detected on the pertechnetate thyroid scan (P = 0.0238). This was not true for a final hyperthyroid outcome (P = 0.7435). The number of detected foci was also significantly associated with the total thyroid volume (P = 0.0006). Findings indicated that the presence of multiple af...Continue Reading

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Citations

Apr 12, 2016·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Mark E PetersonMichael R Broome
Jul 12, 2017·Journal of Feline Medicine and Surgery·Veerle VolckaertKathelijne Peremans
Oct 17, 2017·Journal of Veterinary Internal Medicine·E StockK Vanderperren
Feb 14, 2019·Journal of Veterinary Internal Medicine·Heather L CoveyHarriet M Syme
May 18, 2021·Journal of Veterinary Internal Medicine·Deirdre MullowneyHarriet M Syme

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BETA
biopsies

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