Effect of time-dependent cryotherapy on redox balance of quadriceps injuries

Cryobiology
Marco Aurélio dos Santos SilvaFrank Silva Bezerra

Abstract

Muscle trauma represents a high number of injuries in professional sport and recreation and may occur through several mechanisms. This study aims at analyzing time-dependent effects of cryotherapy on the redox balance in lesioned quadriceps muscles in F1 mice. Twenty male F1 mice were divided into five groups: (a) animals were not subjected to muscle lesioning or treatment (CTR); (b) quadriceps muscle was lesioned without treatment (L); (c) quadriceps muscle was lesioned and treated with cryotherapy for 5 min (LC5); (d) quadriceps muscle was lesioned and treated with cryotherapy for 20 min (LC20); and quadriceps muscle was lesioned and treated with cryotherapy for 40 min (LC40). The mice were euthanized; the quadriceps muscles were collected and subjected to analyses for levels of protein, hydroperoxides, nitrite, catalase (CAT) activity, oxidized glutathione (GSSG) and reduced glutathione (GSH). Protein levels were reduced in L (-39%; p < 0.05), LC5 (-54%; p < 0.05), LC20 (-40%; p < 0.05) and LC40 (-50%; p < 0.05) compared to CTR. There was an increase in lipid peroxidation in L (158%; p < 0.05), LC5 (300%; p < 0.01), LC20 (292%; p < 0.01) and LC40 (362%; p < 0.01) compared to CTR. We observed a significant increase in CAT act...Continue Reading

References

Jan 1, 1992·Free Radical Research Communications·R SchreckP A Baeuerle
Jan 1, 1989·Chemico-biological Interactions·D A Keller, D B Menzel
Jun 1, 1986·Chest·K L Brigham
Jan 1, 1983·Annual Review of Biochemistry·A Meister, M E Anderson
Dec 1, 1980·Clinical Obstetrics and Gynecology·W Droegemuller
Jul 1, 1995·Medicine and Science in Sports and Exercise·J G Tidball
Sep 1, 1994·The American Journal of Sports Medicine·J J CriscoM M Panjabi
Feb 1, 1993·Medicine and Science in Sports and Exercise·H M Alessio
Jan 1, 1996·Free Radical Biology & Medicine·I Rahman, W MacNee
Jan 1, 1996·European Journal of Applied Physiology and Occupational Physiology·A Frankiewicz-JóźkoB Sieradzan-Gabelska
Sep 29, 1998·Mechanisms of Ageing and Development·A Navarro-Arévalo, M J Sánchez-del-Pino
Jan 19, 2000·Clinical Biochemistry·J M MatésI Núñez de Castro
Jul 19, 2000·Thorax·L M Heunks, P N Dekhuijzen
Dec 6, 2001·Cell and Tissue Research·A BurlacuM Simionescu
Jan 15, 2002·American Journal of Physiology. Endocrinology and Metabolism·Marie-Chantal FargesVickie E Baracos
Dec 25, 2003·Thrombosis Research·Hakan FicicilarGulriz Ersoz
Feb 3, 2004·The American Journal of Sports Medicine·Chris BleakleyDomhnall MacAuley
Feb 24, 2004·The American Journal of Sports Medicine·Todd A WarrenKurt P Spindler
Jan 6, 2005·Medicine and Science in Sports and Exercise·Trent A WatsonManohar L Garg
Apr 27, 2005·The American Journal of Sports Medicine·Tero A H JärvinenMarkku Järvinen
Feb 24, 2006·Clinical Physiology and Functional Imaging·Jean Guillaume SteinbergYves Jammes
Feb 28, 2006·European Journal of Pharmacology·Irfan RahmanAruna Kode
Nov 23, 2006·Antioxidants & Redox Signaling·Stefan W RyterAugustine M K Choi
Jun 15, 2007·Developmental Neurobiology·Rebecca McFarlandMichael W Vogel
Jan 1, 1984·The Journal of Orthopaedic and Sports Physical Therapy·S A StrattonR S Francis

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Citations

Oct 12, 2018·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·A B V FurtadoG O Puntel
Nov 12, 2020·Scandinavian Journal of Medicine & Science in Sports·Daniela Pacheco Dos Santos HaupenthalPaulo Cesar Lock Silveira
Jun 19, 2021·World Journal of Clinical Cases·Zi-Ru Wang, Guo-Xin Ni

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