Effect of TiO2 nanoparticles on the reproduction of silkworm

Biological Trace Element Research
Min NiBing Li


Silkworm (Bombyx mori) is an important economic insect and the model insect of Lepidoptera. Because of its high fecundity and short reproduction cycle, it has been widely used in reproduction and development research. The high concentrations of titanium dioxide nanoparticles (TiO2 NPs) show reproductive toxicity, while low concentrations of TiO2 NPs have been used as feed additive and demonstrated significant biological activities. However, whether the low concentrations of TiO2 NPs affect the reproduction of B. mori has not been reported. In this study, the growth and development of gonad of B. mori fed with a low concentration of TiO2 NPs (5 mg/L) were investigated by assessing egg production and expression of reproduction-related genes. The results showed that the low concentration of TiO2 NPs resulted in faster development of the ovaries and testes and more gamete differentiation and formation, with an average increase of 51 eggs per insect and 0.34 × 10(-4) g per egg after the feeding. The expressions of several reproduction-related genes were upregulated, such as the yolk-development-related genes Ovo-781 and vitellogenin (Vg) were increased by 5.33- and 6.77-folds, respectively. This study shows that TiO2 NPs feeding at ...Continue Reading


Jun 22, 2017·Archives of Insect Biochemistry and Physiology·Guofang ShiLihua Zhao
Oct 31, 2018·Environmental Science and Pollution Research International·Nouara AbdelliChen Keping
Feb 12, 2019·Pest Management Science·Xiaoyu ChengBing Li


Nov 1, 1987·Genes & Development·B OliverA P Mahowald
Oct 16, 1999·Nature·J W Truman, L M Riddiford
May 29, 2003·Journal of Insect Physiology·L I. GilbertD S. Richard
Nov 6, 2003·Toxicological Sciences : an Official Journal of the Society of Toxicology·Edilberto BermudezJeffrey I Everitt
Oct 13, 2004·Environmental Research·Valerio Matozzo, Maria Gabriella Marin
Apr 27, 2005·Biological Trace Element Research·Lei ZhengChao Liu
Jun 3, 2005·Biological Trace Element Research·Fashui HongPing Yang
Apr 4, 2006·Journal of Chromatography. a·Shih-Shin LiangShu-Hui Chen
Apr 14, 2007·Environmental Health Perspectives·Vicki H GrassianPeter S Thorne
Jul 20, 2007·Surgical Infections·Michael S CohenIan C Summerhayes
Jul 28, 2007·Journal of Nanoscience and Nanotechnology·N VigneshwaranR H Balasubramanya
Jan 6, 2009·Insect Biochemistry and Molecular Biology·International Silkworm Genome Consortium
May 12, 2009·Current Biology : CB·Kana TanakaKazushige Touhara
Oct 19, 2011·Toxicology and Applied Pharmacology·Nicola A PhilbrookVirginia K Walker
Sep 1, 2012·Journal of Biomaterials Applications·Joana C GuedesIvan B Wall
May 3, 2014·Biological Trace Element Research·Hua ZhangBing Li

Related Concepts

Cell Differentiation Process
Gonadal Structure
Insect Extract
Entire Gonad

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Synapse Loss as Therapeutic Target in MS

As we age, the number of synapses present in the human brain starts to decline, but in neurodegenerative diseases this occurs at an accelerated rate. In MS, it has been shown that there is a reduction in synaptic density, which presents a potential target for treatment. Here is the latest research on synapse loss as a therapeutic target in MS.

Artificial Intelligence in Cardiac Imaging

Artificial intelligence (ai) techniques are increasingly applied to cardiovascular (cv) medicine in cardiac imaging analysis. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

Social Learning

Social learning involves learning new behaviors through observation, imitation and modeling. Follow this feed to stay up to date on the latest research.

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

Single Cell Chromatin Profiling

Techniques like ATAC-seq and CUT&Tag have the potential to allow single cell profiling of chromatin accessibility, histones, and TFs. This will provide novel insight into cellular heterogeneity and cell states. Discover the latest research on single cell chromatin profiling here.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells.