PMID: 9537007Apr 16, 1998Paper

Effect of topical vitamin C on postoperative carbon dioxide laser resurfacing erythema

Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]
T S Alster, T B West

Abstract

Postoperative erythema of several months duration is a universal and problematic side effect of cutaneous carbon dioxide (CO2) laser resurfacing. This study was conducted in order to determine the effectiveness of two formulations of topical ascorbic acid in reducing the degree and duration of post-CO2 laser resurfacing erythema. The application of topical L-ascorbic acid in an aqueous formulation resulted in a significant decrease in post-CO2 laser resurfacing erythema by the eighth postoperative week when compared with laser-irradiated skin that had not received topical vitamin C. The application of topical ascorbic acid in a cream formulation did not result in a significant reduction in post-CO2 laser resurfacing erythema. Topical L-ascorbic acid, when used in an appropriate vehicle and when initiated at an appropriate postoperative period, may decrease the degree and duration of erythema after cutaneous CO2 laser resurfacing. It is presumed that the anti-inflammatory effect of vitamin C is responsible for the clinical changes observed in this study.

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Citations

Feb 1, 2007·Seminars in Plastic Surgery·Gonzalo BlancoJames R Patrinely
Aug 15, 2013·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Koenraad De BoulleDimitrios Stroumpoulis
Jan 27, 2010·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Andrei I Metelitsa, Tina S Alster
Jul 21, 2005·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Patricia K Farris
Jul 2, 1998·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·D H McDanielM Zukowski
Apr 16, 1998·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·C A Nanni, T S Alster
Jun 15, 2013·Otolaryngologic Clinics of North America·James M Hamilton, Edmund A Pribitkin
Sep 20, 2011·Seminars in Cutaneous Medicine and Surgery·Mary Lupo, Leah Jacob
Aug 22, 2009·Clinics in Dermatology·Donald L Bissett
Feb 9, 2010·Dermatologic Therapy·Steven Q WangUli Osterwalder
Dec 8, 2004·Journal of the American Academy of Dermatology·Jeffrey S OrringerGary J Fisher
Aug 25, 1999·Journal of the American Academy of Dermatology·D RatnerD J Fader
Jul 26, 2015·Facial Plastic Surgery Clinics of North America·Amelia Clark, Jill L Hessler
Jul 2, 2016·Clinics in Plastic Surgery·John P McCook
Nov 30, 2007·Dermatologic Therapy·Karen E Burke
May 1, 2019·International Journal of Molecular Sciences·Jung-Won ShinKyung-Chan Park
Jun 13, 2020·American Journal of Clinical Dermatology·Tina S Alster, Monica K Li
Sep 25, 2021·Journal of Cosmetic Dermatology·Christina D EnescuFatima Fahs

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