Effect of traction sutures in the distal esophagus of the rat: a model for esophageal elongation by Foker's method

Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus
Maria Francelina LopesJ Patrício

Abstract

This study aimed to evaluate a rat model of esophageal elongation using traction sutures by the Foker's method. After esophageal division and closure of the distal segment at approximately 4 mm from the cardia, traction sutures were placed for progressive stretching until the 7(th) postoperative day in the experimental group (n = 10), whilst no traction sutures were placed in the esophagus of the control group (n = 10). Clinical outcome as well as macroscopic and microscopic esophageal morphology were evaluated in both groups. All rats survived the surgical procedure and the anesthetic recovery period. Disruption of sutures during the traction period occurred in 20% of the rats, which required reoperation. Integrity of the stretched esophagus was confirmed at autopsy in all animals. In contrast to the control group, the experimental group showed a significantly more elongated (average length 6.10 +/- 1.10 mm versus 3.91 +/- 0.17 mm, (P = 0.0001)) and thicker esophagus (average mass 35.9 +/- 3.31 mg versus 15.6 +/- 1.71 mg in the control group, P = 0.0001). Histopathological examination showed a relatively well preserved morphology of the stretched esophagus. These observations suggest that esophageal stretching by traction sutu...Continue Reading

References

Mar 29, 2003·European Journal of Pediatric Surgery : Official Journal of Austrian Association of Pediatric Surgery ... [et Al] = Zeitschrift Für Kinderchirurgie·G GaglioneS Mazzei
Apr 30, 2003·Journal of Pediatric Surgery·Aayed R Al-QahtaniSandeep K Mayer
Aug 10, 2004·Journal of Pediatric Surgery·Maria Francelina LopesAntónio Pires
Nov 18, 2004·Journal of Pediatric Surgery·Erik D Skarsgard
Mar 17, 2005·Seminars in Pediatric Surgery·John E FokerKhalid M Khan
Sep 1, 2007·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·M F Lopes, M F Botelho

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Citations

Dec 3, 2014·Seminars in Pediatric Surgery·Andrea ConfortiPietro Bagolan
Mar 21, 2015·The Journal of Surgical Research·Satoshi InoueSusumu Eguchi
Jun 12, 2012·Clinics in Perinatology·Shaun M Kunisaki, John E Foker

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