Effect of Transport Parameters and Device Geometry on Extraction Kinetics and Efficiency in Direct Immersion Solid-phase Microextraction

Analytical Chemistry
Md Nazmul AlamJanusz Pawliszyn

Abstract

An alternative strategy to increase mass transfer entails geometry optimization of the extraction systems including design of solid-phase microextraction (SPME) probes. In this work, a computational model was employed to elucidate practical aspects such as efficiency and kinetics of extraction by employing several new geometries. Extraction of a model analyte at static conditions with the configurations, such as thin-film, fiber, coated tip, and nanoparticles, was numerically simulated to obtain an in-depth understanding of the advantages and limitations of each geometry in microextraction and exhaustive modes. The attained results associated with the equilibration time dependency on shape were in good agreement with previously reported experimental observations. They demonstrate that the mass-transfer is highly dependent on the size and shape of the coatings and increases with a decrease in size of the devices particularly rapidly below 10 μm caused by radial diffusion effect. Nevertheless, extractions performed using octadecyl-functionalized magnetic nanoparticles demonstrated that higher enrichment factors are achievable with the use of a fewer number of particles in comparison to factors achieved via exhaustive extraction, ...Continue Reading

References

Jun 15, 2006·Analytical Chemistry·Douglas E Raynie
Sep 24, 2008·Analytica Chimica Acta·Gangfeng Ouyang, Janusz Pawliszyn
Sep 16, 2014·Chemical Communications : Chem Comm·Germán Augusto Gómez-Ríos, Janusz Pawliszyn
Oct 8, 2014·Analytical and Bioanalytical Chemistry·Valérie PichonAudrey Combès
Dec 3, 2014·Journal of Chromatography. a·Nathaly Reyes-GarcésJanusz Pawliszyn
Feb 15, 2017·Analytical Chemistry·N Scott Lynn, Jiří Homola
Nov 9, 2017·Analytical Chemistry·Nathaly Reyes-GarcésJanusz Pawliszyn

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Citations

Oct 27, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Bulat KenessovMiras Derbissalin
Sep 3, 2019·Journal of Mass Spectrometry : JMS·Vinicius Ricardo Acquaro JuniorLuiz Alberto Beraldo Moraes
Apr 22, 2019·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Sângela Nascimento do CarmoEduardo Carasek
Nov 21, 2021·Journal of Separation Science·Sheng PengGangfeng Ouyang

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