PMID: 69831Jul 30, 1977Paper

Effect of triac on the developing heart

Lancet
E G OlsenC M Hawkey

Abstract

Triac (diethanolamine salt of triiodothyroacetic acid) was administered by intramuscular injection to 12 pregnant female rats. These were divided into a control group and three other groups, each receiving different doses of triac. The effect of triac on the hearts of their offspring was studied morphologically. Histological examination showed evidence of only mild hypertrophy, but ultrastructurally, disarray of myocardial fibrils and other changes similar to those observed in patients with hypertrophic cardiomyopathy were found in the litter of the group receiving the highest dose. It is suggested that thyroid function should be studied in patients with obscure cardiac disease.

References

Jun 1, 1975·The Journal of Endocrinology·C SymonsC M Hawkey
Nov 27, 1971·Lancet·C SymonsJ B Wood
Nov 1, 1971·Acta Endocrinologica·H E FarranR Hoffenberg

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Citations

Jan 1, 1992·Journal of Clinical Pharmacology·L ScarpinatoR W Piepho
Nov 1, 1978·British Heart Journal·R BellD C Beton
Mar 1, 1979·British Heart Journal·C Symons
Jul 1, 1982·British Heart Journal·J F Goodwin
Nov 1, 1985·British Heart Journal·D I AltmanS E Levin
Sep 1, 1988·British Heart Journal·A P Fitzpatrick, R W Emanuel
Oct 1, 1978·Postgraduate Medical Journal·C SymonsM Boss
Jun 1, 1986·Postgraduate Medical Journal·E G Olsen
Jan 1, 1991·International Journal of Cardiology·S S Kothari
Jul 1, 1986·International Journal of Cardiology·H K NakazawaK Ito
Jun 1, 1980·The American Journal of Medicine·J F Goodwin
Jun 4, 2017·The Journal of Endocrinology·Stefan GroenewegW Edward Visser
Nov 6, 2003·Microscopy Research and Technique·Paula Juliana FerreiraAnselmo Sigari Moriscot
Jan 1, 1982·Pediatric Cardiology·L A LesterR A Arcilla

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