Effect of two periodontal treatment modalities in patients with uncontrolled type 2 diabetes mellitus: A randomized clinical trial

Journal of Clinical Periodontology
Antonio J QuinteroAntonio Sanz

Abstract

To evaluate the impact of two non-surgical periodontal treatment modalities on metabolic and periodontal clinical parameters in subjects with type 2 diabetes mellitus (T2DM) and poor glycaemic control and chronic periodontitis. A randomized controlled clinical trial was conducted. Ninety-three T2DM subjects with glycosylated haemoglobin (HbA1c) > 7% were randomly assigned to one of two groups receiving scaling with root planing in multiple sessions quadrant-by-quadrant (Q by Q) or within 24 hr (one stage). Periodontal parameters, HbA1c, glycaemia blood levels (FPG) and C-reactive protein (CRP) values were assessed at baseline and at 3 and 6 months post-therapy. At 6 months, HbA1c had decreased by 0.48% in the Q by Q group and by 0.18% in the one-stage group (p = 0.455). After therapy, subjects with an initial HbA1c < 9% showed an increase of 0.31% (p = 0.145), compared with a decrease of 0.88% (p = 0.006) in those with an initial HbA1c ≥ 9%. Periodontal parameters improved significantly (p < 0.0001) post-therapy, with similar results for both treatment modalities. Periodontal therapy had the greatest impact on HbA1c reduction on patients with an HbA1c > 9% regardless of treatment modality. Both modalities resulted in significan...Continue Reading

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Citations

Mar 23, 2019·International Journal of Molecular Sciences·Daniela LiccardoGiuseppe Rengo
Jan 16, 2020·Journal of Applied Oral Science : Revista FOB·Mauricio BaezaJorge Gamonal
Apr 16, 2020·Brazilian Oral Research·Paola CarvajalGiuseppe Alexandre Romito
Apr 16, 2020·Brazilian Oral Research·Ricardo Guimarães FischerMagda Feres
Sep 26, 2020·Diabetes Therapy : Research, Treatment and Education of Diabetes and Related Disorders·Emese BattancsMárk Antal
Jan 23, 2021·Diabetes Therapy : Research, Treatment and Education of Diabetes and Related Disorders·Ya-Fei ChenLong-Jiang Li
Apr 12, 2021·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Yan Zong

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