Effect of ubiquinone on exercise-induced lipid peroxidation in rat tissues

European Journal of Applied Physiology and Occupational Physiology
J Faff, A Frankiewicz-Jóźko

Abstract

Changes in the amount of thiobarbituric acid-reactive substances (TBARS), an index of the lipid peroxidation, were estimated in liver, heart, and the red and white components of gastrocnemius muscle of control (C) and ubiquinone-treated rats (T, 10 mg.kg-1 daily, for 4 weeks) at rest, and 3 and 24 h after running until the rats were exhausted. The activity of creatine kinase in serum and the level of the non-protein sulphhydryl groups (NP-SH) in the above organs were also determined. The running time until exhaustion was longer in T than in C [83.0 (SD 13.8) vs 72.2 (SD 14.8) min, P < 0.05]. The exercise resulted in a significant increase (P < 0.01) in the TBARS amounts in all the tissues obtained from C and in the liver and heart of T. The postexercise amounts of TBARS were significantly higher (P < 0.01) in C than in T. The resting amounts of NP-SH in the heart and liver were significantly higher (P < 0.05) in C compared to T. The exercise led to a decrease in the NP-SH content in the heart and liver (P < 0.05) of C but did not seem to affect the NP-SH contents in these tissues in T. No effect of ubiquinone treatment on postexercise increase in the serum creatine kinase concentration was found. It was concluded that in rats u...Continue Reading

Citations

Feb 21, 2006·Canadian Journal of Applied Physiology = Revue Canadienne De Physiologie Appliquée·Tongjian YouMichael J McKenzie
Jan 16, 2009·Dynamic Medicine : DM·Kelsey Fisher-Wellman, Richard J Bloomer
Jul 9, 2004·Respiratory Physiology & Neurobiology·Jean Guillaume SteinbergYves Jammes
Aug 21, 2013·Chemico-biological Interactions·Viviane GlaserAlexandra Latini
Oct 5, 2007·Wilderness & Environmental Medicine·Usha PanjwaniPratul Kumar Banerjee
May 1, 2019·International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition·Muaz Belviranlı, Nilsel Okudan

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