PMID: 43089Sep 1, 1979

Effect of ultraviolet and gamma-radiation on Herpetomonas samuelpessoai

Acta Tropica
M J EstevesW De Souza


A study was made about the influence of ultraviolet (UV) and gamma-radiations on Herpetomonas samuelpessoai grown either in a chemically defined or in a complex medium. Cells cultivated in defined medium were more sensitive to UV than those from complex medium, as estimated by inhibition of cellular growth. The effect of gamma-radiation, however, was independent of the media in which the cells were grown. Both radiations interfere with the plasma membrane as analysed by parameters such as excretion of cellular material and concanavalin-A-induced agglutination. Doses of UV which inhibit the cellular growth do not interfere with the plasma membrane. With gamma-radiation, however, doses which inhibit cellular growth also interfere with the plasma membrane. These results suggest that for certain applications UV radiation may be an advantage in vaccine production.

Related Concepts

X-Rays, Nuclear
Plasma Membrane
Concanavalin A
Ionizing Radiation
Black Light, Ultraviolet

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