PMID: 9188388Dec 1, 1996Paper

Effect of use of vasopressors in organ donors on immediate function of renal allografts

Journal of Transplant Coordination : Official Publication of the North American Transplant Coordinators Organization (NATCO)
E A O'BrienH C Yang

Abstract

The purpose of this study was to determine whether use of vasopressors in cadaveric donors of renal transplants was associated with an increased prevalence of acute tubular necrosis after kidney transplantation. We compared immediate allograft function in 26 consecutive renal allograft recipients whose donors had been given vasopressors with that in 26 recipients whose donors had nor. The donors treated with vasopressors had been given more than 10 micrograms/kg per minute of dopamine, norepinephrine, or epinephrine, alone or in combination. The groups were matched with respect to donors' age, recipients' disease, and cold ischemic time. The prevalence of immediate allograft function was significantly lower in recipients whose donors had required use of vasopressors (38.5%) than in recipients whose donors had not required vasopressors (65.4%). We conclude that use of vasopressors in kidney donors leads to an increased prevalence of acute tubular necrosis.

Citations

Nov 14, 2015·Transplant International : Official Journal of the European Society for Organ Transplantation·Heiko M MundtPeter Schnülle
Jun 29, 2007·Transplant International : Official Journal of the European Society for Organ Transplantation·Simone HoegerBenito A Yard
Sep 25, 2008·Anesthesiology·Daniel ChappellMarkus Rehm
Apr 22, 2014·The Journal of Trauma and Acute Care Surgery·Bellal JosephPeter Rhee
Jun 28, 2020·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·John BasmajiIan M Ball
May 29, 2004·Transplantation·Meike SchaubFokko J van der Woude
Jun 16, 2004·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Emilio RodrigoManuel Arias
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Nov 6, 2021·Clinical Transplantation·Rishi KothariClaus U Niemann

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