PMID: 690972Jul 1, 1978

Effect of various hexoses on sperm capacitation and penetration of rat eggs in vitro

Journal of Reproduction and Fertility
K Niwa, A Iritani


Fertilization of rat eggs in vitro could not be achieved when epididymal spermatozoa were preincubated and eggs in clots incubated in a chemically defined medium without D-glucose. Very high proportions (84-100%) of eggs examined were undergoing fertilization when 2.78-8.34 mM-D-glucose were included in the medium. The substitution of D-fructose or D-galactose for D-glucose resulted in very poor penetration rates (0-4%), but D-mannose was effective for fertilization (59-99% penetration). Incubations for sperm capacitation and egg fertilization in different media containing the various hexoses showed that rat epididymal spermatozoa could be partly capacitated without hexose, that D-glucose, D-mannose or D-galactose but not D-fructose is effective for sperm capacitation and that only D-glucose and D-mannose supported penetration of eggs in vitro.


Jan 1, 1991·Reproductive Toxicology·V L SlottS D Perreault
Jul 28, 2012·Biology of Reproduction·Summer G GoodsonDeborah A O'Brien
May 3, 2014·BioMed Research International·Alessandra Ferramosca, Vincenzo Zara
Jan 25, 2007·Reproduction : the Official Journal of the Society for the Study of Fertility·G KampG Wegener
Nov 25, 2003·Reproduction in Domestic Animals = Zuchthygiene·H T WuM C Huang
May 14, 2004·International Journal of Andrology·Hiromitsu TanakaY Nishimune
Jul 28, 2017·Molecular Reproduction and Development·Robert J Aitken
Aug 1, 1988·Gamete Research·L R Fraser, K K Ahuja
Jun 19, 2003·American Journal of Physiology. Renal Physiology·Tatiana BlascoVictor Sorribas

Related Concepts

Fertilization in Vitro
Levulosa Ife
Glucose, (beta-D)-Isomer
Sperm Capacitation
Sperm-Zona Pellucida Penetration

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