Effect of ventricular pacing lead position on tricuspid regurgitation: A randomized prospective trial

Heart Rhythm : the Official Journal of the Heart Rhythm Society
J William SchleiferYong-Mei Cha

Abstract

Pacing lead-related tricuspid regurgitation (TR), a recognized complication of ventricular pacing lead implantation, may be affected by lead position or diameter. This study sought to determine the effect of ventricular pacing lead position and diameter on pacing lead-related TR. A randomized prospective trial compared pacing leads in the right ventricular apex (RVA), right ventricular septum (RVS), or left ventricle via the coronary sinus (LV-CS) in a 1:1:1 fashion. Patients undergoing implantable cardioverter-defibrillator lead implantation in the RVA (RVA-ICD) were enrolled in a comparison group. Patients with preexisting moderate or greater TR were excluded. Prospective clinical evaluation, transthoracic echocardiograms, and device interrogation occurred 24 hours and 12 months after device implantation. Sixty-three patients undergoing pacemaker implantation were randomized to RVA, RVS, or LV-CS pacing, and 48 RVA-ICD patients were enrolled as a comparison group. At 12 months, 6 patients (6.4%) developed moderate or greater TR. Moderate or greater TR was not significantly different between groups if analyzed by intention to treat (RVA 5.9%, RVS 10.0%, LV-CS 6.7%, and RVA-ICD 4.8%) or if analyzed by final lead location (RVA 4...Continue Reading

Citations

Feb 15, 2019·Echo Research and Practice·Bushra S RanaPetros Nihoyannopoulos
Aug 23, 2019·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Chin C LeeRahul N Doshi
Aug 11, 2018·Current Treatment Options in Cardiovascular Medicine·Samuel M KimJonathan N Ginns
Apr 21, 2021·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Haran BurriMario Martins Oliveira
Jun 4, 2021·Pacing and Clinical Electrophysiology : PACE·Rob TatumVakhtang Tchantchaleishvili
Aug 30, 2021·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Michael GliksonKlaus K Witte
Aug 30, 2021·European Heart Journal·Michael GliksonUNKNOWN ESC Scientific Document Group

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