PMID: 9631404Jun 19, 1998Paper

Effect of vitamin B6 supplementation in McArdle's disease: a strategic case study

Neuromuscular Disorders : NMD
J PhoenixR H Edwards

Abstract

A patient-blind study into the effect of a 10-week cessation of long-term vitamin B6 supplementation on B6 status and performance in McArdle's disease is reported. Muscle performance was assessed both subjectively and objectively by an ischaemic fatiguing protocol of the adductor pollicis muscle. Nine weeks after withdrawal of supplementation, vitamin B6 status had changed from adequacy to inadequacy and the force loss during the ischaemic fatiguing protocol had increased at all frequencies studied. The patient reported decreased exercise tolerance after 7 weeks and by the tenth week was experiencing an increase in muscle cramps. Vitamin B6 status and muscle performance may be linked in McArdle's disease and there is potential for enhancement of performance by B6 supplementation.

References

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Citations

Jul 6, 2001·Muscle & Nerve·S DiMauro, C Lamperti
Apr 5, 2013·Zeitschrift für Rheumatologie·M Vorgerd, M Deschauer
Jan 16, 2007·Current Neurology and Neuroscience Reports·G Nogales-GadeaA L Andreu
Dec 26, 2003·The New England Journal of Medicine·John Vissing, Ronald G Haller
Oct 30, 2013·Human Gene Therapy·Cathryn S MahBarry J Byrne
Jul 17, 2014·Sports Medicine·Alfredo SantallaAlejandro Lucia
Feb 5, 2000·Neurologic Clinics·S TsujinoS DiMauro
Jul 24, 2014·Journal of Inherited Metabolic Disease·Gisela Nogales-GadeaTomàs Pinós
Nov 13, 2014·The Cochrane Database of Systematic Reviews·Rosaline QuinlivanBenedikt Schoser
May 24, 2006·Annals of Neurology·Ronald G HallerJohn Vissing
Mar 17, 2006·Medicine and Science in Sports and Exercise·Lisa S Krivickas
Apr 11, 2006·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Mark A Tarnopolsky
Dec 16, 1998·Current Opinion in Neurology·S DiMauro, C Bruno
Oct 24, 2002·Current Opinion in Clinical Nutrition and Metabolic Care·Matthias Vorgerd, Jochen Zange
Apr 29, 2015·Human Mutation·Gisela Nogales-GadeaTomàs Pinós
Oct 16, 2015·Physiological Genomics·Gisela Nogales-GadeaAlejandro Lucia
Apr 13, 2004·Current Opinion in Clinical Nutrition and Metabolic Care·Edson Braga LameuRonir Raggio Luiz
Dec 23, 2020·International Journal of Molecular Sciences·Aitana Almodóvar-PayáTomàs Pinós

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