Abstract
Limited data are available regarding cardiac arrhythmias in vitamin D (VitD) deficiency. Therefore, we aimed to assess whether atrial electromechanical delay (AEMD) measured by tissue Doppler imaging (TDI), which is an indicator for atrial fibrillation (AF) development, is prolonged in patients with VitD deficiency as compared to the control group. The effect of vitD replacement on AEMD was also evaluated. In this prospective study a total of 28 VitD-deficient and 56 age-, gender-, and BMI-matched VitD-sufficient healthy participants were enrolled. P-wave dispersion (PWd) was calculated on the 12-lead electrocardiogram. Both intra- and inter-AEMD were calculated by TDI. Measurements were performed at baseline in both groups and were repeated after 6-month replacement therapy in subjects with vitD deficiency. PWd and inter- and left intra-AEMD were significantly prolonged in patients with VitD deficiency compared to the control group (P < 0.001). While serum 25(OH)D levels were significantly and negatively correlated with left intra-AEMD (r = -0.657, P < 0.001), there was a positive correlation between serum 25(OH)D level and PWd (r = 0.523, P < 0.001). The serum 25(OH)D level was found as the independent predictor of the both l...Continue Reading
References
Jan 1, 1986·Journal of Molecular and Cellular Cardiology·M R WaltersP C Riggle
May 20, 1998·American Heart Journal·P E DilaverisP K Toutouzas
Feb 12, 2002·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Miguel A QuiñonesUNKNOWN Doppler Quantification Task Force of the Nomenclature and Standards Committee of the American Society of Echocardiography
Jun 14, 2002·Cardiovascular Research·Maurits AllessieUlrich Schotten
Mar 30, 2005·Circulation·Dalia SomjenNaftali Stern
Jul 28, 2005·The Journal of Steroid Biochemistry and Molecular Biology·Evelyne van Etten, Chantal Mathieu
Dec 27, 2005·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Roberto M LangUNKNOWN European Association of Echocardiography
Feb 26, 2008·Journal of the American College of Cardiology·Brett Burstein, Stanley Nattel
May 20, 2008·American Journal of Physiology. Heart and Circulatory Physiology·Michael S K WongPaul M Vanhoutte
Feb 9, 2010·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Seong-Mi ParkWan-Joo Shim
Sep 30, 2010·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·A John CammUNKNOWN ESC Committee for Practice Guidelines
Jun 8, 2011·The Journal of Clinical Endocrinology and Metabolism·Michael F HolickUNKNOWN Endocrine Society
Jul 8, 2011·The Journal of Clinical Endocrinology and Metabolism·Michael F Holick, Catherine M Gordon
Sep 3, 2011·American Heart Journal·Michiel RienstraThomas J Wang
Jul 25, 2012·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Mehmet DemirMehmet Melek
Oct 9, 2012·Cardiology Journal·Ali DenizAli Oto
Oct 25, 2013·Journal of Cardiovascular Electrophysiology·Dicky A HanafyYi-Jen Chen
Nov 12, 2013·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Wei Ren ChenYun Dai Chen
Jan 18, 2014·Circulation Research·P E Norman, J T Powell
Citations
Feb 6, 2016·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Alvaro AlonsoPamela L Lutsey
Feb 26, 2016·International Urology and Nephrology·Levent DemirtasOzcan Orscelik
Aug 25, 2016·Clinical Cardiology·Zhiwei ZhangTong Liu
Jun 3, 2017·Cardiology in Review·Christos G MihosOrlando Santana
Oct 25, 2017·Journal of Clinical Ultrasound : JCU·Niloofar Akhavan-KhaleghiReza Mohseni-Badalabadi
Dec 9, 2017·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Yap-Hang ChanHung-Fat Tse
Nov 10, 2018·Medicine·Hung-Yu YangYi-Jen Chen
Jul 31, 2021·Journal of Cardiovascular and Thoracic Research·Mehran RahimiFariba Pashazadeh