Effect of vitamin E on IgE antibody formation in mice

Journal of Pharmacobio-dynamics
N InagakiA Koda

Abstract

Effect of vitamin E (alpha-tocopheryl acetate and alpha-tocopheryl nicotinate) on IgE antibody formation in mice was investgiated . Female BALB/c mice were immunized with dinitrophenylated ascaris protein (DNP-As) and aluminium hydroxide gel (alum). Supplementation of vitamin E in diets or oral administration of vitamin E mixed with sesame oil resulted in a suppression of IgE antibody formation. On the contrary to IgE antibody formation, IgM or IgG (hemagglutinin; HA) formation was significantly enhanced. These results indicate that vitamin E is capable of suppressing IgE antibody formation and enhancing non-IgE antibody formation.

Citations

Jan 31, 2006·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Bertha Beatriz Montaño VelázquezRosendo Luria Perez
Oct 31, 2003·Bioscience, Biotechnology, and Biochemistry·Noriko BandoJunji Terao
Feb 11, 2016·International Journal of Molecular Sciences·Nayyar AhmedCenk Suphioglu
Mar 25, 2017·Antioxidants·Kimbell R Duncan, Yuichiro J Suzuki

Related Concepts

3-dl-alpha-tocopheryl nicotinate
Metazoa
Ascaris
Diet
Hemagglutination Test
Immunoglobulin E
Mice, Inbred BALB C
Nicotinic Acids
Passive Cutaneous Anaphylaxis
August Rats

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