Effect of weekend admission for acute myocardial infarction on in-hospital mortality: a retrospective cohort study

International Journal of Cardiology
Toshiaki IsogaiKiyohide Fushimi


No previous nationwide study has examined whether there is a 'weekend effect' of higher mortality after admission for acute myocardial infarction (AMI) when percutaneous coronary intervention (PCI) is easily accessible. Using the Diagnosis Procedure Combination inpatient database in Japan, we identified AMI patients aged ≥20 years who were admitted to acute care hospitals between July 1, 2010 and March 31, 2013. Multivariable regression models fitted with generalized estimating equations were used to determine the association between weekend admission and in-hospital mortality. Eligible patients were also classified into subgroups according to Killip class at admission. Of 111,200 eligible patients, 30,847 patients were admitted on weekends and 80,353 patients on weekdays. Overall, the in-hospital mortality was significantly higher for weekend admission than for weekday admission (13.6% versus 11.4%; P<0.001; unadjusted odds ratio [OR] 1.222; 95% confidence interval [CI] 1.172 to 1.274), despite the higher rate of PCI performed on the day of admission (68.9% versus 64.8%; P<0.001). The association remained significant after adjusting for baseline characteristics, invasive procedures, and medications (adjusted OR 1.144, 95% CI 1...Continue Reading


Mar 27, 2001·Journal of the American College of Cardiology·J V TuK M McDonald
Sep 8, 2001·The New England Journal of Medicine·C M Bell, D A Redelmeier
Jul 28, 2004·The American Journal of Medicine·Peter CramGary E Rosenthal
Jul 28, 2004·The American Journal of Medicine·Chaim M Bell, Donald A Redelmeier
Jan 7, 2005·Circulation Journal : Official Journal of the Japanese Circulation Society·Susumu UiTakaaki Isshiki
Mar 30, 2006·American Heart Journal·Danielle M HenkelVéronique L Roger
Mar 16, 2007·The New England Journal of Medicine·William J KostisUNKNOWN Myocardial Infarction Data Acquisition System (MIDAS 10) Study Group
Nov 27, 2007·Circulation Journal : Official Journal of the Japanese Circulation Society·Kunihiko MatsuiUNKNOWN Japanese Acute Coronary Syndrome Study (JACSS) Investigators
Apr 23, 2008·Circulation·Hani JneidUNKNOWN Get With the Guidelines Steering Committee and Investigators
May 10, 2008·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Patricia KrüthRalf Zahn
Jan 16, 2010·Circulation Journal : Official Journal of the Japanese Circulation Society·Jae Seok HongSun Hee Lee
Jan 30, 2010·Quality & Safety in Health Care·Paul AylinD Bell
Dec 4, 2012·International Journal of Cardiology·Kim Wadt HansenSøren Galatius
Dec 19, 2012·Circulation·Patrick T O'GaraUNKNOWN American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
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