Effect of weight on cardiovascular disease

The American Journal of Clinical Nutrition
W B KannelJ L Cobb

Abstract

Involuntary weight gains worsen all elements of the cardiovascular risk profile, including dyslipidemia, hypertension, insulin-resistant glucose intolerance, left-ventricular hypertrophy, hyperuricemia, and elevated fibrinogen. On the basis of data from the Framingham Heart Study and from other studies, it can be concluded that the degree of overweight is related to the rate of development of cardiovascular disease. After 26 y of follow-up in the Framingham study, each SD increment in relative weight was associated with 15% and 22% increases in cardiovascular events in men and women, respectively. Avoidance of weight gain after the age of 25 y is advisable to reduce cardiovascular mortality. There is a great potential benefit to weight loss, suggesting that weight control as a means for preventing and lessening cardiovascular disease become a national health priority. The optimal weight for avoidance of cardiovascular disease and prolonging life corresponds to a body mass index of 22.6 for men and 21.1 for women.

References

Jan 1, 1994·Reproduction, Nutrition, Development·M YvonT Corring
Nov 15, 2001·Obesity Research·H H Ditschuneit, M Flechtner-Mors
Aug 11, 2004·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·A DueA Astrup
Mar 25, 2005·The British Journal of Nutrition·Manuela P G M LejeuneMargriet S Westerterp-Plantenga
Jul 5, 2006·International Journal of Obesity : Journal of the International Association for the Study of Obesity·J W AndersonL T P Stifler
Jan 8, 2008·The American Journal of Clinical Nutrition·Peter M CliftonManny Noakes

❮ Previous
Next ❯

Citations

Oct 15, 2008·Nature Clinical Practice. Gastroenterology & Hepatology·Peter M Clifton
Oct 29, 2008·Journal of Inherited Metabolic Disease·D M NeyJ A Wolff
Jun 26, 2014·Obesity·Eric A Finkelstein, Eliza Kruger
Jan 2, 2018·International Journal of Endocrinology and Metabolism·Atefeh ZeinolabediniEnayatollah Bakhshi
Apr 15, 2014·Journal of the American College of Nutrition·Paige E MillerVanessa Perez
Oct 17, 2015·International Journal of Environmental Research and Public Health·Haiying GongGuangliang Shan
Oct 24, 2012·Journal of Nutrition and Metabolism·Jennifer B Keogh, Peter M Clifton
Mar 31, 2016·European Journal of Clinical Nutrition·J-W ZhangI M Y Szeto
Jun 14, 2019·The Journal of Nutrition·Amée M BuziauGita D Mishra
Apr 28, 2020·Antioxidants & Redox Signaling·Mathilde Foisy SauvéEmile Levy

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

Related Papers

International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity
S-C LimC-E Tan
Current Opinion in Lipidology
R J GarrisonW B Kannel
JAMA : the Journal of the American Medical Association
T HarrisL Goldman
Acta Medica Scandinavica. Supplementum
M HigginsJ Stokes
© 2021 Meta ULC. All rights reserved