Effect of weight reduction on the severity of lower urinary tract symptoms in obese male patients with benign prostatic hyperplasia: a randomized controlled trial

Korean journal of urology
Chi-Hang YeeChi-Fai Ng

Abstract

We assessed whether weight reduction is an effective intervention for the management of lower urinary tract symptoms (LUTS) and investigated the relationship between obesity and LUTS. This was a prospective randomized controlled trial that enrolled obese men older than 50 years with LUTS. The study period was 52 weeks. All patients received standardized alpha-adrenergic blocker therapy for the treatment of benign prostatic hyperplasia (BPH) during the run-in period. Patients were randomized to receive either a standardized prerecorded video program on the general principle of weight reduction or a comprehensive weight reduction program. Patients were assessed at different time points with symptom assessment, uroflowmetry, transrectal ultrasound, and metabolic assessment. Sixty-five patients were allocated to each study arm. After the study period, no significant difference in weight reduction was found between the two arms. When the pre- and postintervention parameters were compared, none were statistically different between the 2 arms, namely nocturia, International Prostate Symptom Score, quality of life assessment, and uroflowmetry parameters. When the whole study population was taken as a single cohort, these parameters wer...Continue Reading

Citations

Apr 7, 2019·The Cochrane Database of Systematic Reviews·Valter SilvaMaria S Peccin
Nov 20, 2018·The Aging Male : the Official Journal of the International Society for the Study of the Aging Male·Limin YueWeidong Zhang
Sep 8, 2017·The World Journal of Men's Health·Deok Ha SeoJae Seog Hyun

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