PMID: 697707Jul 1, 1978Paper

Effect of X-ray contrast medium on peripheral circulation, arterial blood flow and venous capacity in the lower extremities during phlebography (author's transl)

Basic Research in Cardiology
E van den BergK Barbey

Abstract

The influence of contrast medium (20 ml Meglumine Diatrizoate 65%; Angiografin) on peripheral circulation was studied after injection into the vena saphena magna in 12 patients (mean age 40.5 years) with markedly varicose veins. Pneumatic segment-plethysmography and "mercury-in-rubber" strain-gauge-plethysmography were used to investigate local and systemic effects of contrast medium on intravascular basic volume and pressure-dependent venous capacity. Heart rate was controlled by Ecg-monitoring, venous blood pressure by means of a Schwarzer pressure transducer, and peripheral blood flow by means of pneumatic segment-plethysmography. In addition peripheral vascular resistance was calculated. Local effect of contrast medium on large veins was a small insignificant increase (2.2%) of venous capacity. However, there was a significant increase of additional 10% after recirculation (2 P less than 0.01). Intravascular basic volume showed a significant increase as well (2 P less than 0.01). In addition the calculated increase of total intravascular volume--represented by intravascular basic volume plus venous capacity--was 16.3% related to an intravenous pressure of 70 mm Hg. According to these findings, 20 ml contrast medium enlarges...Continue Reading

References

Oct 1, 1976·Radiology·H W Fischer, F J Colgan
Jul 1, 1971·Acta Radiologica: Diagnosis·P Svendsen, J Wilson
Dec 1, 1969·The American Journal of Roentgenology, Radium Therapy, and Nuclear Medicine·W Delius, U Erikson
Nov 1, 1970·Investigative Radiology·G Ansell
Nov 1, 1970·Investigative Radiology·P Lindgren
Jan 1, 1970·Langenbecks Archiv für Chirurgie·W WenzB Hall
May 1, 1971·Acta Radiologica: Diagnosis·E BoijsenT Hallböök
Apr 1, 1971·The American Journal of Roentgenology, Radium Therapy, and Nuclear Medicine·M N Coel, E C Lasser
Jul 1, 1953·The Journal of Physiology·R J WHITNEY

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