Effect of yeast-derived products and distillers dried grains with solubles (DDGS) on antibody-mediated immune response and gene expression of pattern recognition receptors and cytokines in broiler chickens immunized with T-cell dependent antigens

Poultry Science
M AlizadehB A Slominski

Abstract

This study evaluated the effect of yeast-derived products on innate and antibody mediated immune response in broiler chickens following immunization with sheep red blood cells (SRBC) and bovine serum albumin (BSA). One-day-old male broiler chickens (Ross-308) were randomly assigned to 6 dietary treatments of 9 replicate cages of 5 birds each per treatment. Dietary treatments consisted of a Control diet without antibiotic, and diets containing 11 mg/kg of virginiamycin, 0.25% of yeast cell wall (YCW), 0.2% of a commercial product Maxi-Gen Plus containing processed yeast and nucleotides, 0.05% of nucleotides, or a diet containing 10% of DDGS. On days 21 and 28 post-hatching, 5 birds per treatment were immunized intramuscularly with both SRBC and BSA. One week after each immunization, blood samples were collected. Serum samples were analyzed by hemagglutination test for antibody response to SRBC, and by ELISA for serum IgM and IgG response to BSA. On d 35, 5 birds per treatment were euthanized and the tissue samples from the cecal tonsils were collected to assess the gene expression of toll-like receptors TLR2b, TLR4, and TLR21, monocyte mannose receptor (MMR), and cytokines IL-10, IL-13, IL-4, IL-12p35, and IFN-γ. The results for...Continue Reading

References

Feb 1, 1995·Journal of Nutritional Science and Vitaminology·A A AdjeiA Kulkarni
Jan 28, 1994·Cell·W E Paul, R A Seder
Mar 1, 1994·Stem Cells·S F WolfJ Sypek
Jan 1, 1994·Gut·G K Grimble
Jan 1, 1993·Annual Review of Immunology·D C Parker
Nov 30, 2000·Arthritis Research·C Dong, R A Flavell
Mar 20, 2002·Current Molecular Medicine·V Apostolopoulos, I F McKenzie
May 4, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Scott A McEwen, Paula J Fedorka-Cray
Jan 14, 2003·Annual Review of Immunology·Kiyoshi TakedaShizuo Akira
Mar 5, 2003·Annual Review of Immunology·Thomas A Wynn
Jan 22, 2004·Current Opinion in Immunology·Caetano Reis e Sousa
Apr 28, 2004·Poultry Science·T R Scott
Apr 23, 2005·Poultry Science·J J Dibner, J D Richards
Dec 13, 2005·Clinical and Diagnostic Laboratory Immunology·Hamid R HaghighiShayan Sharif
Aug 1, 2006·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·T FrankicJ Salobir
Jul 7, 2007·Developmental and Comparative Immunology·Megumi HiguchiTsukasa Seya
Oct 5, 2007·Comparative Immunology, Microbiology and Infectious Diseases·G S JensenI Yoon
Oct 24, 2007·British Poultry Science·K C Klasing
Oct 4, 2008·Journal of Immunotherapy·Isabelle MagalhaesMarkus J Maeurer
Dec 17, 2008·Annals of the New York Academy of Sciences·S Vicky Tsoni, Gordon D Brown
Jan 24, 2009·Immunobiology·Umut Gazi, Luisa Martinez-Pomares
Aug 1, 2003·Immunopharmacology and Immunotoxicology·Yuming GuoM A Qureshi
Jan 13, 2010·Immunity·Mirjam SchenkRobert L Modlin
Feb 16, 2010·Nature Reviews. Immunology·Margarida Saraiva, Anne O'Garra
Apr 13, 2010·The Veterinary Journal·Gerard HuyghebaertFilip Van Immerseel
Aug 17, 2010·Poultry Science·C M CoxR A Dalloul
Sep 3, 2010·Cell and Tissue Research·Robert Brownlie, Brenda Allan
Oct 27, 2010·Current Fungal Infection Reports·Frank L van de Veerdonk, Mihai G Netea
Jan 14, 2011·Nutrition Research Reviews·Nadja SauerEva Bauer
Apr 22, 2011·Expert Review of Vaccines·Nikolai Petrovsky, Peter D Cooper
Mar 7, 2012·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Jennifer R Hess, Norman A Greenberg
May 9, 2012·Frontiers in Immunology·Caroline GrönwallGregg J Silverman

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