Effect of Yiqi Huayu Recipe on regeneration process after L5 nerve root compression in rats

Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine
Chong-Jian ZhouMei Liu

Abstract

To study the effect of Yiqi Huayu Recipe on neurons in neuromuscular junction after L5 nerve root compression in rats. By using immunohistochemistry, confocal laser scanning techniques and protein gene product 9.5 as a neuronal marker, the motor endplates were visualized with fluorescein-conjugated alpha-BTX. The effect of Yiqi Huayu Recipe on nerve terminals of neuromuscular junction at 10, 20, 30, 60 days after L5 nerve root compression was observed in rat soleus muscles during regeneration. The overlap areas of terminals and endplates were measured with NIH image technique. As for the aggregates, sprouts, extension of nerve terminal during regeneration, the connecting speed and range of nerve terminal with endplates, as well as the reformation of neuromuscular junctions during regeneration, Yiqi Huayu Recipe group was better than that of the control group. Yiqi Huayu Recipe can promote the hyperplasia of neurons and enhance the regeneration function. It also can accelerate the neuromuscular junction reformation and shorten the process of regeneration.

Citations

Sep 29, 2006·Chinese Journal of Integrative Medicine·Qun-li Wu, Xiao-chun Liang
Sep 24, 2004·Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine·Chong-Jian ZhouQi Shi
Mar 15, 2005·Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine·Yong-Jun WangQi Shi
Nov 12, 2005·Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine·Quan ZhouMei Liu
Mar 15, 2006·Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine·Chong-Jian ZhouQi Shi
Mar 29, 2005·Journal of Huazhong University of Science and Technology. Medical Sciences = Hua Zhong Ke Ji Da Xue Xue Bao. Yi Xue Ying De Wen Ban = Huazhong Keji Daxue Xuebao. Yixue Yingdewen Ban·Farmanullah WazirQinghua Hu

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