Effect on visual outcome after macular hole surgery when staining the internal limiting membrane with indocyanine green dye

Archives of Ophthalmology
Naoichi Horio, M Horiguchi

Abstract

To determine the effect on the visual outcome after macular hole surgery when staining the internal limiting membrane (ILM) with indocyanine green (ICG) dye and to study the mechanism of the adverse effects. We studied 40 eyes of 38 patients with an idiopathic macular hole (size, <0.5 disc diameter; duration, <12 months). The concentration, exposure time, and amount of the ICG solution that was minimally required to make the ILM visible were determined. The patients were randomly divided into group 1 (20 eyes of 19 patients) who underwent ILM peeling without ICG staining, and group 2 (20 eyes of 19 patients) who underwent ILM peeling with ICG staining. Routine examinations were conducted during the 12-month follow-up period. Multifocal electroretinogram, optical coherence tomography, and fluorescein angiography were performed on 31 eyes of 30 patients. The macular hole was closed in all patients. Visual acuity was improved in both groups, but it was significantly better in group 1 (median, 0.85) than in group 2 (median, 0.60; P =.02) after 12 months. The improvement of visual acuity in group 1 (logarithm of the minimum angle of resolution [logMAR] units [SD], 0.82 [0.19]) was significantly better than that in group 2 (logMAR un...Continue Reading

Citations

Oct 23, 2013·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Tom H Williamson, Edward Lee
Oct 1, 2013·International Ophthalmology·Nobuaki HibiHiroko Terasaki
Jun 14, 2013·International Ophthalmology·Anna PraidouArvind Chandna
Dec 17, 2011·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Rasmus EjstrupJ F Kiilgaard
Mar 19, 2005·The British Journal of Ophthalmology·T L Jackson
Jul 1, 2006·The British Journal of Ophthalmology·R TadayoniP Massin
Jan 18, 2005·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·S Dithmar
Jul 13, 2006·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·F RüferJ Roider
Jul 13, 2006·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·C Haritoglou, A Kampik
Dec 17, 2008·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·C HaritoglouF Schüttauf
May 18, 2006·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Timothy Y Y LaiDennis S C Lam
Mar 19, 2014·Ophthalmic Surgery, Lasers & Imaging Retina·Harpreet S WaliaSeenu M Hariprasad
Oct 2, 2015·Journal of Ophthalmology·Mónica Asencio-DuranJesús García-Martínez
Jun 9, 2016·Japanese Journal of Ophthalmology·Masanori NakazawaTaiji Sakamoto
Apr 9, 2013·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Claudine BelleriveMarc Hébert
Sep 28, 2005·Experimental Eye Research·Yan JinMakoto Araie
Jan 11, 2007·Survey of Ophthalmology·Timothy Y Y LaiDennis S C Lam
Nov 6, 2018·Ophthalmic Surgery, Lasers & Imaging Retina·Peter BrachaCaroline R Baumal
Mar 28, 2006·Journal of Cataract and Refractive Surgery·Richard C AllenThomas A Oetting
Mar 13, 2014·International Ophthalmology Clinics·Eric K ChinElliott H Sohn
Mar 13, 2014·International Ophthalmology Clinics·Kevin I Rosenberg, Asheesh Tewari
Jul 13, 2006·Retina·George A Williams
Jun 13, 2015·Asia-Pacific Journal of Ophthalmology·Lee HollandLawrence R Lee
Jun 24, 2008·Survey of Ophthalmology·Ehab Abdelkader, Noemi Lois
Feb 18, 2012·Survey of Ophthalmology·Nieraj JainPrithvi Mruthyunjaya

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