PMID: 6977407Mar 1, 1982Paper

Effective multidrug, multimodality consolidation therapy of adult acute lymphocytic leukemia: a preliminary report

Cancer
R S SteinR D Collins

Abstract

Twelve of 13 adult patients with acute lymphocytic leukemia, acute undifferentiated leukemia, or convoluted T-cell lymphoma (T-cell ALL) who were treated with Adriamycin, vincristine, and prednisone achieved a complete remission. An intensive consolidation regimen was administered. This regimen included Cytosine Arabinoside, L-asparaginase, and multiple courses of CHOP (cyclophosphamide, Adriamycin, vincristine, and prednisone). In addition, cranial irradiation and intrathecal methotrexate were administered. By actuarial estimate, 81% of previously untreated patients who achieved a complete remission will remain in remission for more than two years.

Citations

Nov 8, 1984·The New England Journal of Medicine·A D Jacobs, R P Gale
Jan 1, 1991·Baillière's Clinical Haematology·P Stryckmans, L Debusscher
Aug 1, 1987·Australian and New Zealand Journal of Medicine·J S WileyW H Sawyer
Jan 1, 1985·Hematological Oncology·T BarbuiE Dini

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