Effective Prolonged Therapy with Voriconazole in a Lung Transplant Recipient with Spondylodiscitis Induced by Scedosporium apiospermum.

Case Reports in Infectious Diseases
B LuijkE A van de Graaf

Abstract

Scedosporium/Pseudallescheria species are frequently seen in cystic fibrosis patients. However, disseminated forms after lung transplantation in these patients are rarely seen, but often with poor outcome. In this case report we describe a lung transplant recipient with cystic fibrosis who developed a spondylodiscitis that was caused by Scedosporium apiospermum. The patient was treated with anti-fungal treatment by voriconazole for over three years with a clinical good response and without the need for surgical intervention. To our opinion this is the first anti-fungal treated case of invasive disease caused by Scedosporium/Pseudallescheria in a cystic fibrosis (CF) patient who underwent lung transplantation that survived.

References

Dec 23, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Shahid HusainNina Singh
May 9, 2006·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Françoise SymoensFrédérique Jacobs
Oct 19, 2006·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Michael MuskEli Gabbay
Oct 26, 2006·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·S HusainK R McCurry
Apr 4, 2007·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Hina SahiMarie Budev
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Jan 24, 2008·Antimicrobial Agents and Chemotherapy·Peter TrokeUNKNOWN Global Scedosporium Study Group
Jul 2, 2008·Journal of Neurosurgery. Spine·Fassil B MesfinDarryl Dirisio
Jul 18, 2008·Transplantation Reviews·Amparo Solé, Miguel Salavert
Feb 5, 2009·Medical Mycology·Fotini StripeliM Tsolia
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May 19, 2009·The Spine Journal : Official Journal of the North American Spine Society·Carolina Garcia-VidalPedro Fernandez-Viladrich

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Citations

Apr 18, 2014·Indian Journal of Orthopaedics·Pe Sreedharan NamboothiriVk Visweswaran
Jan 17, 2014·Medical Mycology Case Reports·Nancy E RolfeTodd S Wills
Feb 20, 2014·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·A M TortoranoC Lass-Flörl
Mar 15, 2018·Medical Mycology·Carsten SchwarzUNKNOWN ECMM/ISHAM working group Fungal respiratory infections in Cystic Fibrosis (Fri-CF)
Mar 2, 2018·The Journal of Pharmacology and Experimental Therapeutics·Bénédicte LelièvreJean-Philippe Bouchara

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Methods Mentioned

BETA
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