Effective protection induced by three different versions of the porcine S3Pvac anticysticercosis vaccine against rabbit experimental Taenia pisiformis cysticercosis

Vaccine
Miguel Angel BetancourtI Flores-Perez

Abstract

In an effort to develop an effective and affordable oral vaccine against porcine Taenia solium cysticercosis, the S3Pvac anti-cysticercosis vaccine was expressed in papaya calli. Taenia pisiformis experimental rabbit cysticercosis was used as a model to compare the efficacy of the oral vaccine vs. the injectable S3Pvac-synthetic and S3Pvac-phage versions. Oral S3Pvac-papaya significantly reduced the expected number of hepatic lesions and peritoneal cysticerci to a similar extent than the injectable vaccines. This study reports for the first time an effective oral vaccine against T. pisiformis cysticercosis, possibly useful against porcine T. solium cysticercosis.

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Citations

Dec 12, 2013·Parasite : Journal De La Société Française De Parasitologie·Deying YangGuangyou Yang
Mar 1, 2013·The Journal of Parasitology·Edda SciuttoCarlos Larralde
Nov 13, 2012·Vaccine·Sergio Rosales-MendozaEdda Sciutto
Mar 13, 2015·Molecular Biotechnology·Elizabeth Monreal-EscalanteSergio Rosales-Mendoza
Nov 5, 2016·Veterinary Parasitology·Claudia Hallal-CallerosFernando Iván Flores-Pérez
Jul 15, 2020·Parasitology·Marianna Nascimento ManhaniJulia Maria Costa-Cruz
Aug 28, 2014·Expert Review of Vaccines·Marisela HernándezEdda Sciutto
Feb 15, 2017·Planta·Gladis FragosoEdda Sciutto
Jun 8, 2018·Parasitology Research·Guadalupe NúñezIrene P Del Arenal

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