Effective tissue layer separation of donor cornea for dmek by fluid injection between dscement membrane and corneal stroma: the first cases series

Ceská a slovenská oftalmologie : casopis Ceské oftalmologické spolecnosti a Slovenské oftalmologické spolecnosti
P StodůlkaM Slovák

Abstract

To evaluate clinical outcomes of Descemet Membrane Endothelial Keratoplasty (DMEK) using a novel hydro-separation of donor Descemet membrane (DM) endothelial graft with 6 months follow up. In this retrospective single-center; single surgeon cohort study, 16 consecutive eyes underwent DMEK or combined DMEK and cataract surgery with DMEK donor graft hydro-separation. The hydro-separation method used Ringers solution injected by a syringe with a flat end cannula between DM and corneal stroma to separate DMEK graft from donors cornea. Endothelial cell count, corrected and uncorrected distance visual acuities (CDVA, UDVA), corneal astigmatism and keratometric values were evaluated before and 6 months after the surgery. DMEK grafts were successfully hydro separated, without a membrane tear in all cases and successful adhesion to recipient corneas was achieved in all cases. Overall CDVA improved significantly (p < 0.0001) from preop. logMAR 0.69 (0.45-0.92, 95%CI) to logMAR 0.1 (0.04-0.15) 6 months postop. However UDVA was slightly worse in cataract combined cases 0.38 logMAR (0.18-0.43) vs 0.3 logMAR (0.14-0.61) in DMEK cases at 6 months. Corneal astigmatism K2-K1 improved significantly (p=0.0137) from preop. mean 2.89 D (0.19-0.4...Continue Reading

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