Effective treatment of benign biliary strictures with a removable, fully covered, self-expandable metal stent: A prospective, multicenter European study

United European Gastroenterology Journal
Arthur SchmidtKarel Caca

Abstract

Temporary placement of removable, fully covered, self-expandable metal stents (fcSEMS) for treatment of benign biliary strictures (BBS) has been reported to be effective. However, the optimal extraction time point remains unclear and stent migration has been a major concern. The objective of this study was to evaluate the efficacy and safety of this treatment modality using an fcSEMS with a special antimigration design and prolonged stent indwell time. We performed a prospective, single-arm study at six tertiary care centers in Europe. Patients with BBS underwent endoscopic or percutaneous implantation of an fcSEMS (GORE® VIABIL® Biliary Endoprosthesis, W.L. Gore & Associates, Flagstaff, AZ, USA). The devices were scheduled to be removed nine months later, and patients were to return for follow-up for an additional 15 months. Forty-three patients were enrolled in the study. Stricture etiology was chronic pancreatitis in the majority of patients (57.5%). All fcSEMS were placed successfully, either endoscopically (76.7%) or percutaneously (23.3%). Stent migration was observed in two patients (5.2%). Primary patency of the SEMS prior to removal was 73.0%. All attempted stent removals were successful. At removal, stricture was reso...Continue Reading

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Citations

Sep 8, 2017·Nature Reviews. Disease Primers·Jorg KleeffJohn P Neoptolemos
Dec 6, 2019·Journal of Gastroenterology and Hepatology·Yousuke NakaiBenedict Devereaux
Feb 23, 2019·Expert Review of Gastroenterology & Hepatology·Ali AghdassiMarkus M Lerch
Jul 10, 2019·Frontline Gastroenterology·Mustafa JalalAndrew D Hopper
Aug 17, 2021·Seminars in Interventional Radiology·Adam FangHyun S Kim

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Clinical Trials Mentioned

NCT01343160

Software Mentioned

SAS

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