Effective use of a novel rate-smoothing algorithm in atrial fibrillation by ventricular pacing

European Heart Journal
H J DuckersR Yee

Abstract

It is still unknown whether a fast heart rate or an irregular ventricular response in atrial fibrillation causes tachycardiomyopathy. Reduction in the variability of RR intervals without an increase in heart rate might be an alternative treatment when antiarrhythmic drugs fail to control the irregularity accompanying atrial fibrillation. Eight patients underwent temporary right ventricular pacing, using a novel rate-smoothing algorithm prior to DC cardioversion or His bundle ablation. A rate-smoothing algorithm was utilized by right ventricular apical stimulation. Spontaneous and paced RR intervals during atrial fibrillation were quantified and processed for statistical analysis. The rate-smoothing algorithm resulted in a substantial reduction in the variance of the RR intervals (slow mode 73.1%, fast mode 40.0%) and RR range (slow mode 49.3%, fast mode 34.3%). In contrast to previous algorithms, the mean heart rate during pacing intervention in atrial fibrillation did not change significantly to the heart rate directly preceding the pacemaker intervention (+2%). This initial study of the novel rate-smoothing algorithm shows that pacing intervention is a relatively safe, rapid and reliable alternative therapy for controlling ir...Continue Reading

Citations

Jul 29, 2009·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·John SilberbauerNeil Sulke
Aug 30, 2011·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·N M van Hemel
Jul 27, 2010·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Andrew E Darby, Kenneth C Bilchick
Aug 23, 2006·Pacing and Clinical Electrophysiology : PACE·Gianfranco CiaramitaroGiovanni Battista Del Giudice
Apr 27, 2005·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Youhua Zhang, Todor N Mazgalev
Oct 15, 2013·Medical Hypotheses·Xin-Yao LiuChang-Sheng Ma
May 18, 2007·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Jie LianVolker Lang
Mar 31, 2007·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Jie LianVolker Lang

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