Effectiveness and clinical inertia in patients with antidiabetic therapy

International Journal of Clinical Practice
Manuel Enrique Machado-DuqueJorge Enrique Machado-Alba

Abstract

To establish the effectiveness of antidiabetic therapy and the frequency of clinical inertia in the management of type 2 diabetes mellitus in Colombia. A cross-sectional study with follow-up of patients who had been treated for at least 1 year and were receiving medical consultation for antidiabetic treatment. Effectiveness was established when haemoglobin-A1c levels were <7% and when clinical inertia was reached, which was defined as no therapeutic modifications despite not achieving management controls. Sociodemographic, clinical and pharmacological variables were evaluated, and multivariate analyses were performed. In total, 363 patients with type 2 diabetes mellitus were evaluated, with a mean age of 62.0±12.2 years. A total of 1,016 consultations were evaluated, and the therapy was effective at the end of the follow-up in 57.9% of cases. Clinical inertia was found in 56.8% of patients who did not have metabolic control. The most frequently prescribed medications were metformin (84.0%), glibenclamide (23.4%) and insulin glargine (20.7%). Moreover, 57.6% of the patients were treated with two or more antidiabetic medications. Having metabolic control in the first consult of the follow-up was a protective factor against clinic...Continue Reading

References

Jan 27, 2005·Drugs·Andrew J Krentz, Clifford J Bailey
Jan 29, 2010·Revista Panamericana De Salud Pública = Pan American Journal of Public Health·Jorge E Machado-AlbaHenry Gaviria
Feb 11, 2011·Revista Panamericana De Salud Pública = Pan American Journal of Public Health·Juan Rosas GuzmánUNKNOWN ALAD Consensus Group
Dec 5, 2012·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Elisenda MiróFerran Navarro
Feb 5, 2013·Diabetes Research and Clinical Practice·Uma MudaliarMohammed Ali
Apr 30, 2013·Medicina clínica·José Miguel González-ClementeUNKNOWN Grupo de investigadores del Estudio INERCIA
Aug 16, 2013·Current Medical Research and Opinion·Manel Mata-CasesUNKNOWN GEDAPS (Primary Care Group for the study of Diabetes) of the Catalonian Society of Family and Community Medicine
Aug 24, 2013·The American Journal of Medicine·Athena Philis-Tsimikas
Jan 21, 2014·Diabetes Research and Clinical Practice·Pablo AschnerUNKNOWN IDF Diabetes Atlas
Jan 23, 2014·The Annals of Pharmacotherapy·James DavisDeborah T Juarez
May 2, 2014·The Cochrane Database of Systematic Reviews·Andrew AnglemyerLisa Bero
Aug 13, 2014·Diabetes Therapy : Research, Treatment and Education of Diabetes and Related Disorders·William David StrainPaïvi Paldánius
Feb 6, 2015·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Valerija Bralić LangKsenija Kranjčević
Apr 11, 2015·Medical Journal, Armed Forces India·A S Menon, A I Ahluwalia
Apr 22, 2015·Clinical Diabetes : a Publication of the American Diabetes Association·UNKNOWN American Diabetes Association
Oct 12, 2015·Journal of the American Society of Hypertension : JASH·Manuel Enrique Machado-DuqueJorge Enrique Machado-Alba
Dec 1, 2015·Value in Health Regional Issues·Jorge Enrique Machado-AlbaAndrés Felipe Ruiz

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Citations

Sep 24, 2020·Pharmacology Research & Perspectives·Juan-Sebastian Franco, David Vizcaya
Aug 7, 2020·Journal of Primary Care & Community Health·Andrés Gaviria-MendozaJorge Enrique Machado-Alba
Aug 7, 2021·Antibiotics·Manuel E Machado-DuqueJorge E Machado-Alba

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