Effectiveness and cost-effectiveness of double reading in digital mammography screening: A systematic review and meta-analysis

European Journal of Radiology
Margarita C PossoXavier Bonfill

Abstract

Double reading is the strategy of choice for mammogram interpretation in screening programmes. It remains, however, unknown whether double reading is still the strategy of choice in the context of digital mammography. Our aim was to determine the effectiveness and cost-effectiveness of double reading versus single reading of digital mammograms in screening programmes. We performed a systematic review by searching the PubMed, Embase, and Cochrane Library databases up to April 2017. We used the QUADAS-2 (Quality Assessment of Diagnostic Accuracy Studies) tool and CHEERS (Consolidated Health Economic Evaluation Reporting Standards) checklist to assess the methodological quality of the diagnostic studies and economic evaluations, respectively. A proportion's meta-analysis approach, 95% Confidence Intervals (95% CI) and test of heterogeneity (P values) were used for pooled results. Costs are expressed US$ PPP (United States Dollar purchasing power parities). The PROSPERO ID of this Systematic Review's protocol is CRD42014013804. Of 1473 potentially relevant hits, four high-quality studies were included. The pooled cancer detection rate of double reading was 6.01 per 1000 screens (CI: 4.47‰-7.77‰), and it was 5.65 per 1000 screens (C...Continue Reading

Citations

Apr 11, 2018·Radiology·Sian Taylor-PhillipsAileen Clarke
Sep 1, 2018·Medical Physics·Ziba GandomkarClaudia Mello-Thoms
Feb 15, 2019·International Journal of Cancer. Journal International Du Cancer·Olena MandrikRaul Murillo
Aug 7, 2019·Radiology·Adam YalaConstance Lehman
Aug 8, 2019·Radiology·Despina Kontos, Emily F Conant
Oct 12, 2018·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Jason N ItriSohil H Patel
Aug 25, 2020·Multimedia Tools and Applications·Prashant ShuklaManish Kumar
Aug 31, 2020·Journal of the American College of Radiology : JACR·Ethan O CohenJessica W T Leung
Jan 22, 2022·Technology in Cancer Research & Treatment·Inci Kizildag YirginErkin Aribal

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